Clinical trial Recruiting at 1 site Interventional Ages 20 to 50

Erythropoietin Gel Coating to Boost Dental Implant Stability

Official title: Evaluation of Erythropoietin Gel Effect on Stability of Immediate Implant ( Clinical and Radiographical Study )

Run by Al-Azhar University · NCT06665451 · Data updated 2026-11-12

This study tests whether applying erythropoietin gel to dental implants helps them stabilize better and faster in people needing immediate implants in the front upper jaw.

More Osseointegration trials

Quick facts

Study typeInterventional
Ages20 Years to 50 Years
SexAll
Enrollment24 (estimated)
SponsorAl-Azhar University
Academic / other
Locations1 site (Asyut, Asyut Governorate)
StatusRecruiting
StartedMarch 15, 2025
Main results expectedJune 2026
Study endsJuly 2026
Registry record updatedMay 18, 2026
Trial IDNCT06665451 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults requiring immediate implants in the anterior maxilla after extraction, with good periodontal health and no exclusion criteria listed (e.g., heavy smoking, active infection, certain systemic conditions).

Probably not a fit

Patients with conditions or behaviors that impair bone healing or implant integration may not benefit from the coating.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled trial compares erythropoietin gel-coated implants with non-coated implants placed immediately after extraction in the anterior maxilla. Participants have nonrestorable teeth in the front upper jaw and good periodontal health, with several safety exclusions noted. The trial assesses implant stability clinically and with radiographs to see if the coating improves osseointegration. Enrollment is limited to a single institution in Asyut, Egypt, led by Al-Azhar University.

Why it matters

Potential benefit: If successful, patients could experience faster and more robust implant stabilization, potentially reducing healing time and improving long-term outcomes.

How similar studies have gone: Previous surface coatings have shown variable improvements in osseointegration; this erythropoietin coating approach is being tested for potential added benefit.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement.
* Good general periodontal health and maintenance.

Exclusion Criteria:

* Heavy smokers who smoke more than ten cigarettes per day
* Acute infected socket
* Ant socket with wall defect.
* Pregnency
* Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease.
* Patients who had subjected to intravenous and/or oral bisphosphonate therapy.

Where it's running

  • Faculty of dental medicine Al-Azhar university
    Asyut, Asyut Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.