Erythropoietin Gel Coating to Boost Dental Implant Stability
Official title: Evaluation of Erythropoietin Gel Effect on Stability of Immediate Implant ( Clinical and Radiographical Study )
Run by Al-Azhar University · NCT06665451 · Data updated 2026-11-12
This study tests whether applying erythropoietin gel to dental implants helps them stabilize better and faster in people needing immediate implants in the front upper jaw.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 50 Years |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Asyut, Asyut Governorate) |
| Status | Recruiting |
| Started | March 15, 2025 |
| Main results expected | June 2026 |
| Study ends | July 2026 |
| Registry record updated | May 18, 2026 |
| Trial ID | NCT06665451 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults requiring immediate implants in the anterior maxilla after extraction, with good periodontal health and no exclusion criteria listed (e.g., heavy smoking, active infection, certain systemic conditions).
✕Probably not a fit
Patients with conditions or behaviors that impair bone healing or implant integration may not benefit from the coating.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, controlled trial compares erythropoietin gel-coated implants with non-coated implants placed immediately after extraction in the anterior maxilla. Participants have nonrestorable teeth in the front upper jaw and good periodontal health, with several safety exclusions noted. The trial assesses implant stability clinically and with radiographs to see if the coating improves osseointegration. Enrollment is limited to a single institution in Asyut, Egypt, led by Al-Azhar University.
Why it matters
Potential benefit: If successful, patients could experience faster and more robust implant stabilization, potentially reducing healing time and improving long-term outcomes.
How similar studies have gone: Previous surface coatings have shown variable improvements in osseointegration; this erythropoietin coating approach is being tested for potential added benefit.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement. * Good general periodontal health and maintenance. Exclusion Criteria: * Heavy smokers who smoke more than ten cigarettes per day * Acute infected socket * Ant socket with wall defect. * Pregnency * Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease. * Patients who had subjected to intravenous and/or oral bisphosphonate therapy.
Where it's running
-
Faculty of dental medicine Al-Azhar university
Asyut, Asyut Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Ahmed Mohsen Principle investigator
- Email: a7medmohsen453@gmail.com
- Phone: 00201020994802
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.