Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Pain relief for rib fractures using ultrasound-guided nerve block

Official title: Ultrasound Guided Serratus Anterior Plane Block Versus Standard Therapy for Analgesic Relief of Rib Fractures in the Emergency Department

Run by WellSpan Health · NCT05748366 · Data updated 2026-11-12

This study is testing if a special ultrasound-guided nerve block can help people with multiple rib fractures feel less pain and breathe better compared to just using regular pain medications.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorWellSpan Health
Academic / other
Locations1 site (York, Pennsylvania)
StatusRecruiting
StartedMarch 31, 2023
Main results expectedMarch 31, 2027
Study endsJune 30, 2027
Registry record updatedJuly 18, 2025
Trial IDNCT05748366 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults over 18 with unilateral, acute rib fractures requiring pain management in the emergency department.

Probably not a fit

Patients under 18, those with significant distracting injuries, or those unable to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of the serratus anterior plane block (SAPB) in managing pain for patients with multiple rib fractures in the emergency department. It compares the outcomes of patients receiving SAPB to those treated with standard analgesic medications alone. The study aims to assess not only pain relief but also respiratory function and overall clinical outcomes, including the need for additional care and length of hospital stay. By utilizing ultrasound guidance, the trial seeks to evaluate the safety and feasibility of this innovative pain management technique in an acute care setting.

Why it matters

Potential benefit: If successful, this approach could significantly improve pain management and recovery for patients with rib fractures, potentially reducing the need for opioids.

How similar studies have gone: Previous studies have shown promising results with similar ultrasound-guided nerve block techniques for pain management, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>18 years
* \>1 Unilateral, acute rib fractures diagnosed on x-ray or CT imaging
* Patient presenting to the WellSpan York Hospital ED
* Patient requiring IV analgesia or oral opioid to control pain related to rib fractures

Exclusion Criteria:

* Age \<18 years
* Inability to provide informed consent
* Allergy to local anesthesia
* Subsequent visit for rib fractures
* Patients taken emergently to the OR or discharged from the ED
* Significant distracting injuries/polytrauma that would not be expected to be responsive to analgesia from SAPB and confound pain scores, i.e. long bone fractures, intraabdominal injuries, etc.

Where it's running

  • Wellspan Health York Hospital
    York, Pennsylvania, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.