Pain relief for rib fractures using ultrasound-guided nerve block
Official title: Ultrasound Guided Serratus Anterior Plane Block Versus Standard Therapy for Analgesic Relief of Rib Fractures in the Emergency Department
Run by WellSpan Health · NCT05748366 · Data updated 2026-11-12
This study is testing if a special ultrasound-guided nerve block can help people with multiple rib fractures feel less pain and breathe better compared to just using regular pain medications.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | WellSpan Health Academic / other |
| Locations | 1 site (York, Pennsylvania) |
| Status | Recruiting |
| Started | March 31, 2023 |
| Main results expected | March 31, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | July 18, 2025 |
| Trial ID | NCT05748366 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 with unilateral, acute rib fractures requiring pain management in the emergency department.
✕Probably not a fit
Patients under 18, those with significant distracting injuries, or those unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of the serratus anterior plane block (SAPB) in managing pain for patients with multiple rib fractures in the emergency department. It compares the outcomes of patients receiving SAPB to those treated with standard analgesic medications alone. The study aims to assess not only pain relief but also respiratory function and overall clinical outcomes, including the need for additional care and length of hospital stay. By utilizing ultrasound guidance, the trial seeks to evaluate the safety and feasibility of this innovative pain management technique in an acute care setting.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and recovery for patients with rib fractures, potentially reducing the need for opioids.
How similar studies have gone: Previous studies have shown promising results with similar ultrasound-guided nerve block techniques for pain management, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 years * \>1 Unilateral, acute rib fractures diagnosed on x-ray or CT imaging * Patient presenting to the WellSpan York Hospital ED * Patient requiring IV analgesia or oral opioid to control pain related to rib fractures Exclusion Criteria: * Age \<18 years * Inability to provide informed consent * Allergy to local anesthesia * Subsequent visit for rib fractures * Patients taken emergently to the OR or discharged from the ED * Significant distracting injuries/polytrauma that would not be expected to be responsive to analgesia from SAPB and confound pain scores, i.e. long bone fractures, intraabdominal injuries, etc.
Where it's running
-
Wellspan Health York Hospital
York, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Daniel Kreider, MD — WellSpan Health
- Study coordinator: Daniel Kreider, MD
- Email: dkreider3@wellspan.org
- Phone: 717-851-5817
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
RibFix Titan implants for stabilizing rib fractures
This follow-up will see if using the RibFix Titan implant is safe and helps adults with single or multiple rib fractures recover after surgical fixation.
-
Morbidity and mortality after serratus anterior plane block for unilateral anterolateral rib fractures
This study tests whether giving a serratus anterior plane block (SAPB) within 24 hours to adults with multiple unilateral anterolateral rib fractures can reduce complications like pneumonia, shorten hospital stay, improve discharge outcomes, and lower death compared with usual opioid-based pain control.
-
Freezing Nerves to Relieve Pain from Rib Fractures
This study is testing if freezing the nerves can help people with rib fractures feel less pain compared to a fake treatment.
-
Using cryoablation to improve pain control after rib fracture surgery
This study is testing if using cryoablation on certain nerves after rib fracture surgery can help patients feel less pain and use fewer pain medications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.