Clinical trial Recruiting at 2 sites Interventional Ages 18 to 99

Enhancing speech rehabilitation for stroke patients using brain stimulation

Official title: Using tDCS in Speech-based Stroke Rehabilitation

Run by NYU Langone Health · NCT03452202 · Data updated 2026-11-12

This study is testing if combining speech therapy with a gentle brain stimulation technique can help stroke patients with speech difficulties improve their communication skills.

Quick facts

Study typeInterventional
Ages18 Years to 99 Years
SexAll
Enrollment24 (estimated)
SponsorNYU Langone Health
Academic / other
Locations2 sites (New York, New York and 1 other locations)
StatusRecruiting
StartedJanuary 11, 2019
Main results expectedApril 30, 2027
Study endsApril 30, 2027
Registry record updatedJune 3, 2026
Trial IDNCT03452202 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are right-handed, monolingual English speakers who have experienced a single left-hemisphere stroke and are at least six months post-event.

Probably not a fit

Patients with laryngeal voice disorders, dysarthria, or a history of speech impairment prior to their stroke may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the effectiveness of combining behavioral treatment for acquired speech impairment with transcranial direct current stimulation (tDCS) in patients with apraxia of speech following a stroke. The approach involves delivering low-intensity electrical current to the scalp to potentially enhance speech motor learning, a method that has shown promise in other areas of stroke rehabilitation. Participants will undergo a series of single-case experimental designs to assess the impact of this combined treatment. The study focuses on right-handed, monolingual individuals who are at least six months post-stroke and have a clinical diagnosis of apraxia of speech.

Why it matters

Potential benefit: If successful, this approach could significantly improve speech rehabilitation outcomes for stroke patients with apraxia of speech.

How similar studies have gone: While tDCS has shown success in enhancing motor learning in other rehabilitation domains, its application in speech motor learning is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Right-handed
* Monolingual (English)
* Single left-hemisphere CVA
* A minimum of six months post-stroke
* Clinical diagnosis of apraxia of speech
* Normal speech perception
* Passing score on the hearing screening.

Exclusion Criteria:

* Diagnosis of laryngeal voice disorder
* Dysarthria
* History of speech impairment prior to CVA
* Presence of potential tDCS risk factors: damaged skin at site of stimulation;
* Presence of electrically or magnetically activated implant (including pacemaker);
* metal in any part of their body;
* history of medication-resistant epilepsy in the family;
* past history of seizures or unexplained spells of loss of consciousness.

Where it's running

  • New York University School of Medicine
    New York, New York, United States
    Recruiting
  • Burke Rehabilitation Hospital
    White Plains, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Adam Buchwald, MD — NYU Langone Health
  • Study coordinator: Buchwald Lab
  • Email: buchwald-lab@nyu.edu

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.