ENDO1000 — a UK-wide project on endometriosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

ENDO1000 is a UK-wide, longitudinal observational project that combines mobile app or web-based symptom tracking with clinical records and biosample collection to create a large, multimodal dataset. Participants aged 16 and over with a clinical diagnosis of endometriosis within the past 10 years are invited to report symptoms and provide samples remotely where possible. The project excludes pregnant people and those with certain infections or severe coagulation disorders because of sample-postage and safety rules. Collected data aim to support data-driven research on diagnosis, pain management, and personalized treatment pathways over time.

Why it matters

Who can join: the full rules

INCLUSION CRITERIA

1. Aged 16 or over
2. Participants who confirm that they have received a clinical diagnosis of endometriosis (based on MRI, ultrasound or laparoscopy) within the last 10 years
3. Living within the UK
4. Willing and able to consent to installing and using the mobile ENDO1000 app on their smartphone or use our web-based equivalent.

EXCLUSION CRITERIA

1. Pregnant
2. Known severe coagulation disorder
3. Known active Hepatitis B/C and/or HIV (due to Royal Mail restrictions on biospecimen postage)

Where it's running

• University of Edinburgh
  Edinburgh, United Kingdom Recruiting

Study contacts

• Principal investigator: Andrew W Horne, PhD, MB ChB — University of Edinburgh
• Study coordinator: Ann M Doust, DipN
• Email: ann.doust@ed.ac.uk
• Phone: +4478910643488

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing different techniques to treat endometriosis

  This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.

  Recruiting TriHealth Inc. · Cincinnati, Ohio · NCT06414083

• Postoperative Pain Trajectories After Endometriosis Surgery

  This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

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• Imaging endometriosis with a special PET tracer in adult women

  This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07876648

• Fiber supplement for digestive symptoms in endometriosis

  A fiber-based supplement is being tested to see if it is safe and helps with gut and vaginal microbiomes and digestive symptoms in women with endometriosis.

  Recruiting LOAM Science · San Francisco, California · NCT07875062

• Stellate ganglion block and dexmedetomidine for better sleep after gynecologic laparoscopy

  The study tests whether giving a preoperative stellate ganglion block plus intraoperative dexmedetomidine improves sleep after laparoscopic gynecologic surgery in women.

  Recruiting The Second People's Hospital of Huai'an · Huai'an, Jiangsu · NCT07860203

• Atypical Endometriosis: Histology, Immunophenotype and Molecular Features

  Researchers will look at how endometriotic tissue that looks atypical under the microscope relates to clinical features and ultrasound findings to better separate benign from potentially atypical lesions.

  Recruiting Casa di Cura Dott. Pederzoli · Peschiera del Garda, Verona · NCT07816133

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.