Electro-acupuncture for women with reduced ovarian function
Official title: Effect of Electro-acupuncture on Ovarian Function and Outcome of IVF-ET of Women With Diminished Ovarian Reserve:a Randomized Controlled Clinical Trial
Run by Huazhong University of Science and Technology · NCT04972877 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests if electro-acupuncture can help women with reduced ovarian function feel better and improve their chances of success with in vitro fertilization (IVF).
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 338 (estimated) |
| Sponsor | Huazhong University of Science and Technology Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT04972877 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women under 40 years old with low ovarian reserve who are planning to undergo IVF.
✕Probably not a fit
Patients with certain reproductive system abnormalities or other significant endocrine diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial investigates the effects of electro-acupuncture on women diagnosed with diminished ovarian reserve (DOR), a condition that can lead to reduced fertility. Participants will undergo 24 sessions of electro-acupuncture over a period of 2-3 months, with baseline measurements taken before and after treatment to assess changes in ovarian function and overall well-being. The study aims to determine if electro-acupuncture can improve outcomes for women undergoing in vitro fertilization (IVF) by enhancing ovarian function.
Why it matters
Potential benefit: If successful, this treatment could improve ovarian function and increase the chances of successful IVF outcomes for women with diminished ovarian reserve.
How similar studies have gone: Previous studies have shown promising results for acupuncture in improving ovarian function, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age \< 40, will undergo IVF-ET; 2. Low ovarian reserve: Antral follicle count (AFC)\<7, or AMH\<1.1ng/ml; or has a history of poor ovarian response: in the last hyper stimulation cycle, the number of retrieved oocytes\<3; 3. Spouse' semen examination is normal, or after semen prewash can reach the standard of common IVF or Intracytoplasmic Sperm Injection(ICSI). Exclusion Criteria: 1. Male with azoospermia; 2. Male/female's chromosome is abnormal; 3. Adenomyosis, uterine fibroids, endometrial polyps, scar uterine, reproductive system tuberculosis, oviduct effusion, pelvic lesions such as ovarian endometriosis cyst or tumor; 4. Female has other endocrine disease: thyroid diseases, hyperprolactinemia, insulin resistance, diabetes, adrenal diseases, etc. 5. Definitively diagnosed autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, antiphospholipid syndrome; 6. Other pathogenesis that leads to recurrent miscarriage or agnogenic recurrent miscarriage; 7. A history of cancer and has received radiotherapy and chemotherapy; 8. Had acupuncture treatment in recent 3 months; 9. Unwilling to sign the informed consent of this study.
Where it's running
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Department of Integrated Traditional Chinese and Western Medicine Tongji hospital of Huazhong University of Science and Technology
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Dongmei Huang, doctor — Department of Integrated Traditional Chinese and Western Medicine Tongji hospital of Huazhong University of Science and Technology
- Study coordinator: Dongmei Huang, doctor
- Email: hdmjcr@qq.com
- Phone: 13971578190
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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G-CSF for DOR in women undergoing IVF
This trial tests whether G-CSF shots can improve IVF outcomes for women with diminished ovarian reserve.
-
Bushen Yiqi herbal formula plus DHEA for women with diminished ovarian reserve
This trial will test whether adding the Bushen Yiqi herbal formula to DHEA helps women aged 20–40 with diminished ovarian reserve improve ovarian function and symptoms.
-
Tongue and gut bacteria patterns in women with diminished ovarian reserve
This study will see if tongue-coating and gut bacteria differ between women with diminished ovarian reserve and healthy women and whether those bacteria relate to ovarian hormone levels.
-
Vitamin C to improve IVF outcomes for women with diminished ovarian reserve
This trial will test whether taking vitamin C during IVF improves pregnancy and live-birth chances for women with diminished ovarian reserve.
-
Using NMN to improve IVF outcomes in women with low ovarian reserve
This study is testing if a supplement called NMN can help improve pregnancy success rates for women with low ovarian reserve who are going through IVF.
-
Pulsatile FSH treatment for women with obesity to improve fertility
This study is testing if a new way of giving hormone treatment can help women with obesity who are having trouble getting pregnant.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.