Effects of sourdough fermentation on blood sugar in prediabetic adults

Effects of Natural Sourdough Fermentation Duration and Acid Development on Postprandial Blood Glucose in Prediabetic Adults

Not applicable Interventional Arizona State University · NCT06925451

This study is testing if eating sourdough bread that has been fermented for longer can help lower blood sugar levels in adults with prediabetes.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages18 Years and up
SexAll
SponsorArizona State University Academic / other
Locations1 site (Phoenix, Arizona)
Trial IDNCT06925451 on ClinicalTrials.gov

What this trial studies

This trial investigates how different fermentation durations of sourdough bread affect postprandial blood glucose levels in adults with prediabetes. Participants will consume sourdough bread with varying fermentation times after fasting, allowing researchers to measure the impact on their blood sugar response. The study aims to determine if longer fermentation times lead to improved glycemic control compared to traditional yeast bread. By focusing on naturally fermented sourdough, the trial seeks to explore a dietary intervention that could enhance metabolic health in prediabetic individuals.

Who should consider this trial

Good fit: Ideal candidates for this study are adults diagnosed with prediabetes who are not taking diabetic medications.

Not a fit: Patients who are on medications affecting blood glucose or those following a carbohydrate-restricted diet may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a dietary strategy to help manage blood sugar levels in prediabetic patients.

How similar studies have performed: While few studies have specifically examined the effects of naturally fermented sourdough on prediabetes, related research on fermented foods and glycemic control suggests potential benefits.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* prediabetes; not on metformin; no known food allergies or sensitivities; not supplementing pre/post biotics

Exclusion Criteria:

* following diet that restricts carbohydrates; medication use affecting blood glucose; acute illness; smoker; pregnant; lactating; GI tract surgery; not willing to follow protocol

Where this trial is running

Phoenix, Arizona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Insulin Resistancefermentationpre-diabetessourdough breadpost-prandial glycemia
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.