Effects of resistance training intensity on heart health in hypertensive women
Acute and Chronic Effects of Resistance Training Intensity on Cardiovascular Parameters of Postmenopausal Women With Systemic Arterial Hypertension
This study is testing how different levels of weightlifting can improve heart health in postmenopausal women with high blood pressure.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 50 Years to 65 Years |
| Sex | Female |
| Sponsor | University of Sao Paulo Academic / other |
| Locations | 1 site (Ribeirão Preto, São Paulo) |
| Trial ID | NCT06538454 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to investigate how different intensities of resistance training (RT) affect cardiovascular parameters in postmenopausal women with systemic arterial hypertension. Participants will engage in two RT sessions at varying intensities (60% and 80% of their one repetition maximum) to assess changes in blood pressure, heart rate, heart rate variability, and endothelial function. The study will include both acute and chronic evaluations to provide a comprehensive understanding of the impact of RT intensity on these health metrics. Measurements will be taken before, immediately after, and one hour post-exercise to capture the hypotensive effects of the training.
Who should consider this trial
Good fit: Ideal candidates for this study are postmenopausal women aged 50 to 65 who have a diagnosis of hypertension and are physically inactive.
Not a fit: Patients with significant cardiovascular issues, obesity, or those on specific heart medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to optimized resistance training guidelines that improve cardiovascular health in hypertensive postmenopausal women.
How similar studies have performed: While there is existing research on resistance training and hypertension, this study's direct comparison of different intensities in this specific population is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women with 50 to 65 old years; * Postmenopausal diagnosis (amenorrhea for 12 months or more); * Previous diagnosis of hypertension and treat with medications; * Physically inactive. Exclusion Criteria: * History of other cardiovascular problems (heart failure, heart attack, stroke, etc); * Grade II obesity (BMI ≥ 35 kg/m²); * Medications (beta-blockers and/or non-dihydropyridine calcium channel blockers); * Systolic blood pressure at rest above 160 mmHg and/or dyastolic blood presure above 105 mmHg; * Unable to perform resistance exercise due to musculoskeletal or cognitive reasons.
Where this trial is running
Ribeirão Preto, São Paulo
- Laboratório de Fisiologia do Exercício e Metabolismo — Ribeirão Preto, São Paulo, Brazil (Recruiting)
Study contacts
- Study coordinator: Leonardo S Gonçalves
- Email: leonardo.edfisica@usp.br
- Phone: 16981806105
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.