Effects of Milrinone on Right Ventricular Function in Heart Surgery Patients

Effect of Milrinone on the Right Ventricular Strain in Cardiac Surgery

Observational Konkuk University Medical Center · NCT06077721

This study is testing if the medication milrinone can improve heart function in patients with good left heart performance who are having heart surgery.

Quick facts

Study typeObservational
Enrollment41 (estimated)
Ages20 Years and up
SexAll
SponsorKonkuk University Medical Center Academic / other
Locations1 site (Seoul)
Trial IDNCT06077721 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the impact of milrinone on right ventricular strain in patients undergoing elective cardiac surgery. By measuring changes in right ventricular systolic performance before and after milrinone administration, the study seeks to determine if this medication can enhance cardiac function in this specific patient population. The study will involve patients with a left ventricular ejection fraction greater than 50% who meet the inclusion criteria and provide informed consent.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled for elective cardiac surgery with a left ventricular ejection fraction greater than 50%.

Not a fit: Patients with preoperative cardiac dysrhythmia, those requiring intra-aortic balloon pump support, or those using other inotropic agents may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management of right ventricular function in patients undergoing cardiac surgery.

How similar studies have performed: While the specific approach of this study may be novel, similar studies have explored the effects of milrinone on cardiac function, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patient agree and provide written informed consent.
* patient undergoing elective cardiac surgery
* preoperative LV EF\>50% (TTE)

Exclusion Criteria:

* preoperative cardiac dysrhythmia
* preoperative IABP
* use of other inotropic agents

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ischemic Heart DiseaseValvular Heart DiseaseMilrinonestrainsystolic function
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.