Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Effects of exercise on heart and lung responses in post-COVID-19 patients

Official title: Acute Cardiovascular Responses to a Single Exercise Session in Patients With Post-Covid-19 Syndrome

Run by University of Nove de Julho · NCT06248151 · Data updated 2026-11-12

This study tests how exercise affects heart and lung responses in people who have had COVID-19, comparing those with ongoing symptoms to those without.

More Post-Acute COVID-19 Syndrome trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorUniversity of Nove de Julho
Academic / other
Locations1 site (São Paulo)
StatusRecruiting
StartedFebruary 15, 2024
Main results expectedDecember 30, 2024
Study endsJuly 30, 2025
Registry record updatedDecember 4, 2024
Trial IDNCT06248151 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals who have had a positive COVID-19 test and are experiencing persistent symptoms of post-COVID-19 syndrome.

Probably not a fit

Patients who have not experienced COVID-19 or those with high cardiovascular risk may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the immediate cardiovascular and perceptual responses to a single exercise session in individuals who have experienced COVID-19, focusing on those with and without persistent symptoms. Participants will engage in both an exercise session, which includes aerobic and strength exercises, and a control session where they remain seated. Measurements such as blood pressure, heart rate, and oxygen saturation will be taken before, during, and after each session to assess their responses. The study employs a crossover design to ensure that each participant serves as their own control.

Why it matters

Potential benefit: If successful, this study could help identify effective exercise interventions for improving cardiovascular health in post-COVID-19 patients.

How similar studies have gone: While there is emerging research on post-COVID-19 rehabilitation, this specific approach to assessing acute responses to exercise in this population is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Post-Covid Syndrome group:

* have had a positive RT-PCR test for Covid-19;
* present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO);
* have the cognitive and physical capacity to perform the exercises; It is
* low cardiovascular risk classification according to the American College of Sports Medicine criteria.

Healthy group:

* not present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO);
* have the cognitive and physical capacity to perform the exercises; It is
* low cardiovascular risk classification according to the American College of Sports Medicine criteria.

Where it's running

  • Universidade Nove de Julho
    São Paulo, Brazil
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.