Investigating dysfunctional breathing in patients with post COVID-19 condition

Dysfunctional Breathing in Patients With Post COVID-19 Condition

Observational Karolinska Institutet · NCT06776263

This study is trying to see how breathing problems affect people who are dealing with long-term symptoms after having COVID-19.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorKarolinska Institutet Academic / other
Locations2 sites (Stockholm, Solna and 1 other locations)
Trial IDNCT06776263 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the signs and symptoms of dysfunctional breathing in patients suffering from post COVID-19 condition. It will utilize various measurements and questionnaires to identify and assess dysfunctional breathing, focusing on the underlying mechanisms and patient experiences. The study is part of a larger project, ReCOV, which takes a holistic approach to understanding the consequences of COVID-19. Participants will be recruited from the ReCov cohort and evaluated for their physical and psychological recovery over time.

Who should consider this trial

Good fit: Ideal candidates are patients reporting persistent respiratory problems with specific scores on the mMRC or Nijmegen scales.

Not a fit: Patients unable to perform the required measurements due to cognitive or physical impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved assessment and management strategies for patients experiencing dysfunctional breathing after COVID-19.

How similar studies have performed: While this approach is part of a larger multi-disciplinary project, similar studies have shown promise in understanding post-viral syndromes, though this specific focus on dysfunctional breathing is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients that state that they have persistent respiratory problems, have 2 or higher on mMRC scale or 23 and over on the Nijmegen scale will be included.

Exclusion Criteria:

* Not able to perform the measurements because of cognitive or physical impairments, ongoing intervention of breathing exercises.

Where this trial is running

Stockholm, Solna and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post COVID-19 ConditionDysfunctional BreathingBreathing Pattern DisorderPost-Acute COVID-19 SyndromeRespirationDyspneaSigns and Symptoms, RespiratoryHyperventilation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.