Clinical trial Recruiting at 2 sites Interventional Ages 25 to 75 Women only

Effects of exercise during chemotherapy in women with breast cancer

Official title: Effects of a Physical Exercise Intervention at the Molecular Systemic and Tumor Level Performed During Neoadjuvant Chemotherapy in Women With Breast Cancer

Run by Universidad Europea de Madrid · NCT04135586 · Data updated 2026-11-12

This study tests if a tough exercise program can help women with triple-negative breast cancer feel better and improve their physical health while they are getting chemotherapy.

More Physical Exercise trials

Quick facts

Study typeInterventional
Ages25 Years to 75 Years
SexWomen only
Enrollment80 (estimated)
SponsorUniversidad Europea de Madrid
Academic / other
Drugs / interventionschemotherapy
Locations2 sites (Madrid and 1 other locations)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedNovember 1, 2026
Study endsDecember 1, 2026
Registry record updatedJune 27, 2024
Trial IDNCT04135586 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women diagnosed with triple-negative breast cancer who are receiving neoadjuvant chemotherapy at the specified hospital.

Probably not a fit

Patients who do not have triple-negative breast cancer or are not undergoing neoadjuvant chemotherapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses the impact of an intense physical exercise program on women with triple-negative breast cancer undergoing neoadjuvant chemotherapy. Participants in the intervention group will engage in high-intensity interval training and resistance exercises, while a control group will not meet the minimum exercise recommendations set by the World Health Organization. The primary aim is to evaluate improvements in physical capacity, with secondary outcomes including body composition, quality of life, and levels of depression and anxiety.

Why it matters

Potential benefit: If successful, this intervention could enhance physical capacity and overall well-being in women undergoing chemotherapy for breast cancer.

How similar studies have gone: Previous studies have shown varying success with exercise interventions during chemotherapy, but this specific approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with breast carcinoma in the 'Hospital Universitario Quirónsalud de Pozuelo' (Madrid, Spain) and following neoadjuvant therapy in the aforementioned center.
* Must have triple negative breast cancer (i.e., negative for estrogen receptors, progesterone receptors, and excess HER2 protein) of size \> or equal to 15 mm

Exclusion Criteria:

* Not meeting all of the above.

Where it's running

  • Hospital Universitario Quirónsalud de Pozuelo (HUQP)
    Madrid, Spain
    Recruiting
  • Lgcortijo@Gmail.Com
    Madrid, Spain
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.