Effects of electrical stimulation on fatigue in healthy individuals

Neuromodulation and Its Effects on Muscle Activity and Fatigue

Not applicable Interventional University of Oklahoma · NCT05487131

This study tests if a mild electrical current applied to the neck can help healthy adults feel less tired and improve their muscle performance.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorUniversity of Oklahoma Academic / other
Locations1 site (Norman, Oklahoma)
Trial IDNCT05487131 on ClinicalTrials.gov

What this trial studies

This project investigates the impact of transcutaneous spinal direct current stimulation (TsDCS) on functional capacity and muscle activation in healthy individuals aged 18 to 50. Participants will undergo one familiarization session followed by three experimental sessions where their fatigability and motor function will be assessed. The study aims to explore how a weak electrical current applied to the neck or thoracic area influences fatigue levels and muscle performance.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy individuals aged 18 to 50 without any neuromuscular diseases or metal implants.

Not a fit: Patients with metal implants, joint replacements, or skin hypersensitivity may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into non-invasive methods to enhance functional capacity and reduce fatigue in healthy individuals.

How similar studies have performed: While the approach of using electrical stimulation for fatigue is explored in various contexts, this specific application in healthy aging is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Healthy individuals between 18 and 50 years old

Exclusion Criteria:

Metal implants or joint replacement. Presence of neuromuscular disease. Skin hypersensitivity.

Where this trial is running

Norman, Oklahoma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy AgingFatigueTranscutaneous spinal direct current stimulationTsDCSFatigability
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.