Effect of Silicone Oil on Retinal Electrical Function Measured by Multifocal ERG
Official title: Effect of Silicon Oil on Retinal Electrical Functions in Patients With Rhegmatogenous Retinal Detatchment Using Multifocal Electroretinogram .
Run by Minia University · NCT07609628 · Data updated 2026-11-12
This study tests how silicone oil as a temporary eye tamponade affects retinal function in people with a primary rhegmatogenous retinal detachment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Minia University Academic / other |
| Locations | 1 site (Minya, Minya Governorate) |
| Status | Recruiting |
| Started | February 1, 2026 |
| Main results expected | July 15, 2026 |
| Study ends | August 1, 2026 |
| Registry record updated | May 27, 2026 |
| Trial ID | NCT07609628 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with primary rhegmatogenous retinal detachment who have not had prior intraocular surgery and do not have excluded ocular diseases or poor fixation.
✕Probably not a fit
Patients with emulsified silicone oil, complicated detachments, or significant ocular comorbidities may not experience measurable retinal function benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial will use multifocal electroretinography to map retinal function after silicone oil tamponade in eyes with primary rhegmatogenous retinal detachment. It is an interventional study without a listed phase, focusing on the electrical responses of the retina in the presence of silicone oil. The goal is to understand whether silicone oil alters central retinal function compared with baseline or expected postoperative recovery. Participants will have specific eligibility criteria, including a history of primary RRD and no prior intraocular surgery. Exclusion criteria ensure that confounding ocular conditions and emulsified silicone oil do not bias results.
Why it matters
Potential benefit: If successful, the study could clarify how silicone oil impacts retinal function after detachment surgery, potentially guiding tamponade choices.
How similar studies have gone: Previous experience with silicone oil tamponade addresses safety and outcomes, but data on direct functional electrical changes are limited and this study explores a more novel functional assessment.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Patients with primary rhegmatogenous retinal detachment Exclusion Criteria: * Patients with history of previous intraocular surgery. * Patients with combined traction-rhegmatogenous retinal detachment * Patients with ocular disease as glaucoma ,degenerative myopia,age related macular degeneration * Patients with poor fixation. * Uncooperative patients. * Patients with retinopathy. * emulsified SO or complicated SO removal were excluded from this study
Where it's running
-
Faculty of medicine
Minya, Minya Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Amany Nady Mohammed Mohammed, Resident
- Email: drmonmonnady92@gmail.com
- Phone: +201151849593
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Human amniotic membrane patches to seal inferior retinal breaks
This trial will try using human amniotic membrane (hAM) patches during vitrectomy to seal inferior retinal breaks in adults with rhegmatogenous retinal detachment.
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Comparing vitrectomy alone to vitrectomy with cataract removal for retinal detachment
This study is testing whether doing just vitrectomy or adding cataract removal helps older adults with retinal detachment see better and have fewer problems after surgery.
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This study is testing if a medication called methotrexate can help prevent vision loss from complications after retinal detachment surgery in adults.
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Topical netarsudil to prevent scar-like membranes after retinal detachment surgery
This trial will test whether once-daily netarsudil eye drops given before and after vitrectomy can help prevent proliferative vitreoretinopathy (scar tissue) in adults with retinal detachment or established PVR.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.