Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Effect of Silicone Oil on Retinal Electrical Function Measured by Multifocal ERG

Official title: Effect of Silicon Oil on Retinal Electrical Functions in Patients With Rhegmatogenous Retinal Detatchment Using Multifocal Electroretinogram .

Run by Minia University · NCT07609628 · Data updated 2026-11-12

This study tests how silicone oil as a temporary eye tamponade affects retinal function in people with a primary rhegmatogenous retinal detachment.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment50 (estimated)
SponsorMinia University
Academic / other
Locations1 site (Minya, Minya Governorate)
StatusRecruiting
StartedFebruary 1, 2026
Main results expectedJuly 15, 2026
Study endsAugust 1, 2026
Registry record updatedMay 27, 2026
Trial IDNCT07609628 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with primary rhegmatogenous retinal detachment who have not had prior intraocular surgery and do not have excluded ocular diseases or poor fixation.

Probably not a fit

Patients with emulsified silicone oil, complicated detachments, or significant ocular comorbidities may not experience measurable retinal function benefits.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial will use multifocal electroretinography to map retinal function after silicone oil tamponade in eyes with primary rhegmatogenous retinal detachment. It is an interventional study without a listed phase, focusing on the electrical responses of the retina in the presence of silicone oil. The goal is to understand whether silicone oil alters central retinal function compared with baseline or expected postoperative recovery. Participants will have specific eligibility criteria, including a history of primary RRD and no prior intraocular surgery. Exclusion criteria ensure that confounding ocular conditions and emulsified silicone oil do not bias results.

Why it matters

Potential benefit: If successful, the study could clarify how silicone oil impacts retinal function after detachment surgery, potentially guiding tamponade choices.

How similar studies have gone: Previous experience with silicone oil tamponade addresses safety and outcomes, but data on direct functional electrical changes are limited and this study explores a more novel functional assessment.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Patients with primary rhegmatogenous retinal detachment

Exclusion Criteria:

* Patients with history of previous intraocular surgery.
* Patients with combined traction-rhegmatogenous retinal detachment
* Patients with ocular disease as glaucoma ,degenerative myopia,age related macular degeneration
* Patients with poor fixation.
* Uncooperative patients.
* Patients with retinopathy.
* emulsified SO or complicated SO removal were excluded from this study

Where it's running

  • Faculty of medicine
    Minya, Minya Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.