Comparing laser and cryotherapy for retinal detachment treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of two surgical techniques, laser photocoagulation and transscleral cryopexy, in treating rhegmatogenous retinal detachment using pneumatic retinopexy. Forty patients with specific retinal tears will be randomly assigned to receive one of the two interventions during the same surgical procedure. The study aims to assess both anatomical and functional outcomes following treatment, with careful monitoring of intraocular pressure and retinal perfusion. Patients will be informed about the risks and benefits of the procedures before participation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with rhegmatogenous retinal detachment with one or more tears within two clock hours, limited to the upper half of the retina

Exclusion Criteria:

* Patients with tears in the lower half of the retina
* Patients with multiple retinal tears covering more than two clock hours
* Patients with developed proliferative vitreoretinopathy
* Patients with vitreous hemorrhage
* Patients with opaque optical media due to other conditions that could obstruct a detailed fundus examination or the procedure itself
* Patients unable to follow postoperative head positioning instructions
* Patients under age of 18 years

Where it's running

• Clinical Hospital Center, Split
  Split, Croatia Recruiting

Study contacts

• Principal investigator: Ivan Borjan, MD — Clinical Hospital Center, Split
• Study coordinator: Ivan Borjan, MD
• Email: ivan.borjan@kbsplit.hr
• Phone: +385981715350

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of Silicone Oil on Retinal Electrical Function Measured by Multifocal ERG

  This study tests how silicone oil as a temporary eye tamponade affects retinal function in people with a primary rhegmatogenous retinal detachment.

  Recruiting Minia University · Minya, Minya Governorate · NCT07609628

• Human amniotic membrane patches to seal inferior retinal breaks

  This trial will try using human amniotic membrane (hAM) patches during vitrectomy to seal inferior retinal breaks in adults with rhegmatogenous retinal detachment.

  Recruiting Eye & ENT Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT07081945

• Comparing vitrectomy alone to vitrectomy with cataract removal for retinal detachment

  This study is testing whether doing just vitrectomy or adding cataract removal helps older adults with retinal detachment see better and have fewer problems after surgery.

  Recruiting at 30 sites Phase 3 Queen's University, Belfast · Aylesbury and 29 other locations · NCT06997874

• Preventing vision loss after retinal detachment surgery with methotrexate

  This study is testing if a medication called methotrexate can help prevent vision loss from complications after retinal detachment surgery in adults.

  Recruiting Phase 2 Cincinnati Eye Institute, Southwest Ohio · Cincinnati, Ohio · NCT06541574

• Topical netarsudil to prevent scar-like membranes after retinal detachment surgery

  This trial will test whether once-daily netarsudil eye drops given before and after vitrectomy can help prevent proliferative vitreoretinopathy (scar tissue) in adults with retinal detachment or established PVR.

  Recruiting Phase 1/2 Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT06033703

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.