Comparing laser and cryotherapy for retinal detachment treatment
Comparison of Anatomical and Functional Outcomes of Laser Photocoagulation and Cryopexy in Patients with Rhegmatogenous Retinal Detachment Treated with Pneumatic Retinopexy: a Randomized Clinical Trial
This study is testing whether laser treatment or freezing treatment works better for fixing retinal detachment in patients with certain types of retinal tears.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Clinical Hospital Center, Split Academic / other |
| Locations | 1 site (Split) |
| Trial ID | NCT06694259 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two surgical techniques, laser photocoagulation and transscleral cryopexy, in treating rhegmatogenous retinal detachment using pneumatic retinopexy. Forty patients with specific retinal tears will be randomly assigned to receive one of the two interventions during the same surgical procedure. The study aims to assess both anatomical and functional outcomes following treatment, with careful monitoring of intraocular pressure and retinal perfusion. Patients will be informed about the risks and benefits of the procedures before participation.
Who should consider this trial
Good fit: Ideal candidates are adults with rhegmatogenous retinal detachment involving one or more tears in the upper half of the retina.
Not a fit: Patients with lower retinal tears, multiple tears, or other complicating factors may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve surgical outcomes and vision preservation for patients with retinal detachment.
How similar studies have performed: Previous studies have shown varying success with similar surgical techniques, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with rhegmatogenous retinal detachment with one or more tears within two clock hours, limited to the upper half of the retina Exclusion Criteria: * Patients with tears in the lower half of the retina * Patients with multiple retinal tears covering more than two clock hours * Patients with developed proliferative vitreoretinopathy * Patients with vitreous hemorrhage * Patients with opaque optical media due to other conditions that could obstruct a detailed fundus examination or the procedure itself * Patients unable to follow postoperative head positioning instructions * Patients under age of 18 years
Where this trial is running
Split
- Clinical Hospital Center, Split — Split, Croatia (Recruiting)
Study contacts
- Principal investigator: Ivan Borjan, MD — Clinical Hospital Center, Split
- Study coordinator: Ivan Borjan, MD
- Email: ivan.borjan@kbsplit.hr
- Phone: +385981715350
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.