Comparing vitrectomy alone to vitrectomy with cataract removal for retinal detachment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to determine the best surgical approach for treating rhegmatogenous retinal detachment (RRD) in adults aged 50 and older who have not previously undergone cataract surgery. It compares outcomes between patients receiving only vitrectomy and those undergoing a combined procedure of vitrectomy and cataract removal. The study will assess the effectiveness of each approach in terms of retinal reattachment and vision improvement. Participants will be monitored for complications and overall visual outcomes following their respective surgeries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults ≥50 years of age
* Non-highly myopic (\< -6 diopters; ≤26.5 mm axial length) phakic RRD
* Naive to previous vitreoretinal surgery
* Pars plana vitrectomy is planned to repair their RRD

Exclusion Criteria:

* Presence of a "formed/established cataract." A "formed/established cataract" is defined as a cataract that, based on the Age-Related Eye Disease Study (AREDS) Research Group, is graded as nuclear sclerosis of \>3 and/or if there is an anterior cortical cataract and/or a subcapsular posterior cataract involving the visual axis.
* Pseudophakia or aphakia
* High myopia (≥ -6 diopters; \>26.5 mm axial length)
* Giant retinal tear (i.e. presence of one or more retinal tears of \>3 clock hours in size)
* Retinal dialysis
* Inclusion in an investigational drug study
* Declined consent for participation

Where it's running

• Buckinghamshire Healthcare NHS Trust
  Aylesbury, United Kingdom Recruiting
• Belfast Health and Social Care Trust
  Belfast, United Kingdom Recruiting
• Sandwell and West Birmingham Hospitals NHS Trust
  Birmingham, United Kingdom Recruiting
• Bradford Teaching Hospitals NHS Foundation Trust
  Bradford, United Kingdom Recruiting
• University Hospitals Bristol NHS Foundation Trust
  Bristol, United Kingdom Recruiting
• County Durham and Darlington NHS Foundation Trust
  Darlington, United Kingdom Recruiting

Study contacts

• Principal investigator: Noemi Lois — Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK
• Study coordinator: Colette Jackson
• Email: colette.jackson@nictu.hscni.net
• Phone: +44 28 96151447

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Topical netarsudil to prevent scar-like membranes after retinal detachment surgery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.