Effect of Movement Mobilization on Knee Osteoarthritis Symptoms
Investigation of the Effect of Movement Mobilization Concept on Quantitative Sensory Parameters, Pain, Muscle Activation Levels in Patients With Knee Osteoarthritis
This study is testing if specific movement exercises can help people with knee osteoarthritis feel less pain and move better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 36 (estimated) |
| Ages | 45 Years to 70 Years |
| Sex | All |
| Sponsor | Istinye University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06527313 on ClinicalTrials.gov |
What this trial studies
This study investigates how a movement mobilization concept can affect sensory perception, pain levels, and muscle activation in patients suffering from knee osteoarthritis. It employs quantitative sensory assessments and electromyographic evaluations to objectively measure changes in sensory perception and muscle function. The goal is to develop targeted rehabilitation interventions that can improve mobility and reduce pain for individuals with this condition. Participants will engage in specific exercises and treatments, including movement mobilization and taping techniques.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50 to 70 with a confirmed diagnosis of knee osteoarthritis who can walk independently and have moderate pain levels.
Not a fit: Patients with severe systemic diseases, neurological disorders, or those who have undergone recent steroid injections may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and mobility for patients with knee osteoarthritis.
How similar studies have performed: Other studies have shown promising results using similar movement mobilization techniques for managing osteoarthritis symptoms.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosing knee OA according to the American College of Rheumatology (ACR) criteria (Primary knee OA diagnosis) * Stage 2 or 3 patients according to Kellgren-Lawrence radiological staging criteria * Patients with a disease duration of 6 months or longer * Participants aged between 50 and 70 * Being able to walk without using assistive devices * Body mass index is below 35 kg/m² * Pain intensity must be between 3 and 7 according to the Numerical Pain Rating Scale * Not having received physiotherapy in the last year. Exclusion Criteria: * Infiltration with steroids or local anesthetics in the year before the patient entered the study or during follow-up * Obtaining the indication for surgery * Severe hearing, vision and speech impairment * Having serious systemic and cardiovascular diseases that prevent exercise * Having a neurological disease * Having a lower extremity deformity (severe varus or valgus deformity, significant joint instability and other orthopedic problems requiring surgical intervention) * Patients with acute knee inflammation * Having any disorder, syndrome or disease that may cause myofascial or neuropathic pain in the lower extremities, such as lumbar radiculopathy, meralgia paresthetica or Saphenous nerve compression. * Cognitive deficit (Alzheimer's, dementia) revealed in the clinical history.
Where this trial is running
Istanbul
- Istinye University — Istanbul, Turkey (Recruiting)
Study contacts
- Study coordinator: Burcu Işıkcı, 1
- Email: burcu.pamukcu@istinye.edu.tr
- Phone: 905397441212
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.