Effect of mask and high flow oxygen on preoxygenation in obese patients
The Effect of Mask Combined With High Flow Oxygen on Preoxygenation During Induction of General Anesthesia in Obese Patients
NA · Henan Provincial People's Hospital · NCT06562660
This study tests how smoking affects the amount of time obese men can safely go without breathing during anesthesia when given high-flow oxygen beforehand.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | Male |
| Sponsor | Henan Provincial People's Hospital (other) |
| Locations | 1 site (Zhengzhou) |
| Trial ID | NCT06562660 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of smoking on the duration of safe apnoea times during general anesthesia induction in obese male patients. Participants are divided into two groups based on their smoking status: smokers and non-smokers. Both groups receive high-flow nasal oxygen for five minutes before anesthesia induction, after which their oxygen saturation levels are monitored until they drop to 95%. The goal is to determine how smoking affects preoxygenation in this specific patient population.
Who should consider this trial
Good fit: Ideal candidates are male patients aged 18 to 80 with a BMI of 30 kg/m2 or higher who are undergoing elective non-thoracic surgery.
Not a fit: Patients with unstable hemodynamics, airway inflammatory diseases, or those requiring awake intubation due to cervical spine issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve preoxygenation strategies for obese patients undergoing surgery, potentially reducing the risk of airway-related incidents.
How similar studies have performed: While the use of high-flow nasal oxygen in anesthesia is established, the specific focus on smoking's impact in obese males is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Participants ranged in age from 18 to 80 with BMI≥30 kg/m2. 2. Participants are male obese patients undergoing elective non-thoracic surgery Exclusion Criteria : 1. patients were kept awake during the intubation due to cervical spine pathology. 2. Patients with unstable hemodynamics. 3. Patients with airway inflammatory diseases, including asthma, chronic obstructive pulmonary disease (COPD), lung cancer, pulmonary fibrosis and cystic fibrosis. 4. Patients with upper respiratory infection and nasal blockage. 5. Patients with Hypersensitivity to the drug.
Where this trial is running
Zhengzhou
- Wanghuabing — Zhengzhou, China (RECRUITING)
Study contacts
- Study coordinator: huabing wang
- Email: 642221283@qq.com
- Phone: +8618538706687
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Obese, High-Flow Nasal Oxygen, Obese Men, Smoking