Effect of Cardiorespiratory Changes on Carotid Flow Time During Lung Resection
Official title: Noninvasive Perioperative Hemodynamic Monitoring In Thoracic Surgery: A Prospective Observational Study
Run by University of Valencia · NCT07808749 · Data updated 2026-11-12
This study tests how anesthesia-related changes during lung surgery affect carotid flow time to see if it reflects fluid status and heart pre-load for patients undergoing thoracoscopic lung resection.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Valencia Academic / other |
| Locations | 1 site (Valencia) |
| Status | Recruiting |
| Started | January 27, 2025 |
| Main results expected | December 17, 2026 |
| Study ends | March 15, 2027 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT07808749 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults scheduled for thoracoscopic lung resection without carotid stenosis or abnormal carotid anatomy and without conditions that would interfere with carotid imaging.
✕Probably not a fit
Patients with carotid abnormalities or other excluded conditions may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how intraoperative cardiorespiratory alterations—such as anesthesia, patient positioning, one-lung ventilation, open chest, capnothorax, lung recruitment, and volume expansion—impact corrected carotid flow time. The goal is to understand the relationship between carotid flow time and cardiac output in the surgical setting and to evaluate whether carotid flow time can predict fluid responsiveness during one-lung ventilation. Secondary analyses compare hemodynamic and ventilatory variables across sex, ventilation protocol, operative side, recruitment tolerance, and fluid responsiveness. The study enrolls patients undergoing thoracoscopic lung resection and excludes those with carotid pathology or significant carotid anatomy issues that would hinder visualization.
Why it matters
Potential benefit: If successful, carotid flow time could become a noninvasive tool to guide fluid management and assess preload during lung surgery.
How similar studies have gone: Previous work shows carotid flow time can reflect preload in some settings, but its use during complex thoracic surgery is less established and this study explores that gap.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients scheduled to undergo thoracosocpic lung resection surgery Exclusion Criteria: * carotid stenosis or abnormal anatomy of carotid artery that prevents visualization, emphysema, arrythmia
Where it's running
-
Hospital General Valencia
Valencia, Spain Recruiting
Study contacts
- Study coordinator: Manuel Granell Gil Prof.
- Email: margry@uv.es
- Phone: 609232031
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.