Clinical trial Recruiting at 1 site Interventional Ages 50 to 80

Effect of brain stimulation and therapy on fatigue after stroke

Official title: The Effects of Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue

Run by The Hong Kong Polytechnic University · NCT06810817 · Data updated 2026-11-12

This study is testing if brain stimulation combined with therapy can help stroke survivors feel less tired and improve their overall well-being.

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment75 (estimated)
SponsorThe Hong Kong Polytechnic University
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedOctober 28, 2024
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedSeptember 17, 2026
Trial IDNCT06810817 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals diagnosed with stroke at least 6 months prior, experiencing significant fatigue, and who are cognitively intact.

Probably not a fit

Patients with unstable medical conditions, other neurological diseases, or contraindications to tDCS may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the impact of transcranial direct current stimulation (tDCS) combined with a cognitive behavioral program on fatigue in stroke survivors. Participants will be randomly assigned to one of three groups: one receiving tDCS and cognitive behavioral therapy with home-based physical training, another receiving sham tDCS with the same therapy, and a third group receiving only home-based physical training. The aim is to determine the effectiveness of these interventions in reducing fatigue and improving related outcomes in individuals who have experienced a stroke.

Why it matters

Potential benefit: If successful, this approach could significantly reduce fatigue and improve quality of life for stroke survivors.

How similar studies have gone: While the combination of tDCS and cognitive behavioral therapy is a novel approach, similar studies have shown promise in addressing fatigue in other conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosed with stroke at least 6 months ago
* Fatigue Assessment Scale score ≥20
* cognitively intact

Exclusion Criteria:

* Unstable medical conditions leading to fatigue
* Under any clinical trials
* with any other neurological diseases
* history of transient ischemic attack
* Contraindications to tDCS

Where it's running

  • The Hong Kong Polytechnic University
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.