Effect of brain stimulation and therapy on fatigue after stroke

The Effects of Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue

NA · The Hong Kong Polytechnic University · NCT06810817

This study is testing if brain stimulation combined with therapy can help stroke survivors feel less tired and improve their overall well-being.

Quick facts

PhaseNA
Study typeInterventional
Enrollment75 (estimated)
Ages50 Years to 80 Years
SexAll
SponsorThe Hong Kong Polytechnic University (other)
Locations1 site (Hong Kong)
Trial IDNCT06810817 on ClinicalTrials.gov

What this trial studies

This study evaluates the impact of transcranial direct current stimulation (tDCS) combined with a cognitive behavioral program on fatigue in stroke survivors. Participants will be randomly assigned to one of three groups: one receiving tDCS and cognitive behavioral therapy with home-based physical training, another receiving sham tDCS with the same therapy, and a third group receiving only home-based physical training. The aim is to determine the effectiveness of these interventions in reducing fatigue and improving related outcomes in individuals who have experienced a stroke.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with stroke at least 6 months prior, experiencing significant fatigue, and who are cognitively intact.

Not a fit: Patients with unstable medical conditions, other neurological diseases, or contraindications to tDCS may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce fatigue and improve quality of life for stroke survivors.

How similar studies have performed: While the combination of tDCS and cognitive behavioral therapy is a novel approach, similar studies have shown promise in addressing fatigue in other conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosed with stroke at least 6 months ago
* Fatigue Assessment Scale score ≥20
* cognitively intact

Exclusion Criteria:

* Unstable medical conditions leading to fatigue
* Under any clinical trials
* with any other neurological diseases
* history of transient ischemic attack
* Contraindications to tDCS

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.