Effect of brain stimulation and therapy on fatigue after stroke
Official title: The Effects of Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue
Run by The Hong Kong Polytechnic University · NCT06810817 · Data updated 2026-11-12
This study is testing if brain stimulation combined with therapy can help stroke survivors feel less tired and improve their overall well-being.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 80 Years |
| Sex | All |
| Enrollment | 75 (estimated) |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | October 28, 2024 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | September 17, 2026 |
| Trial ID | NCT06810817 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals diagnosed with stroke at least 6 months prior, experiencing significant fatigue, and who are cognitively intact.
✕Probably not a fit
Patients with unstable medical conditions, other neurological diseases, or contraindications to tDCS may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the impact of transcranial direct current stimulation (tDCS) combined with a cognitive behavioral program on fatigue in stroke survivors. Participants will be randomly assigned to one of three groups: one receiving tDCS and cognitive behavioral therapy with home-based physical training, another receiving sham tDCS with the same therapy, and a third group receiving only home-based physical training. The aim is to determine the effectiveness of these interventions in reducing fatigue and improving related outcomes in individuals who have experienced a stroke.
Why it matters
Potential benefit: If successful, this approach could significantly reduce fatigue and improve quality of life for stroke survivors.
How similar studies have gone: While the combination of tDCS and cognitive behavioral therapy is a novel approach, similar studies have shown promise in addressing fatigue in other conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosed with stroke at least 6 months ago * Fatigue Assessment Scale score ≥20 * cognitively intact Exclusion Criteria: * Unstable medical conditions leading to fatigue * Under any clinical trials * with any other neurological diseases * history of transient ischemic attack * Contraindications to tDCS
Where it's running
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The Hong Kong Polytechnic University
Hong Kong, Hong Kong Recruiting
Study contacts
- Study coordinator: Shamay NG
- Email: shamay.ng@polyu.edu.hk
- Phone: 852-2766-4889
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.