Clinical trial Recruiting at 1 site Interventional Ages 18 to 85

Early VR-Based Rehab for the Arm After Acute Ischemic Stroke

Official title: Effectiveness of Early Intervention With Virtual Reality-based Interactive Rehabilitation on Upper Extremity Muscle Strength, Cognitive Status, Hospital Anxiety and Exercise Self-efficacy in Patients With Acute Ischemic Stroke: A Randomized Controlled Trial

Run by Tri-Service General Hospital (TSGH) · NCT07674329 · Data updated 2026-11-12

This trial tests whether starting virtual reality–based arm rehabilitation within 24 hours of an acute ischemic stroke helps improve arm strength, thinking skills, anxiety, and confidence to exercise compared with standard rehab.

Quick facts

Study typeInterventional
Ages18 Years to 85 Years
SexAll
Enrollment100 (estimated)
SponsorTri-Service General Hospital (TSGH)
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedMarch 7, 2025
Main results expectedOctober 1, 2026
Study endsOctober 1, 2026
Registry record updatedJune 29, 2026
Trial IDNCT07674329 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–85 with acute ischemic stroke diagnosed within the past 10 days, able to participate in rehabilitation and without major comorbidities limiting upper-limb function.

Probably not a fit

Patients with severe visual impairment, visuospatial neglect, other disabling conditions affecting the upper limb, recurrent strokes, seizures during the study, or inability to cooperate may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a VR motion-sensing rehabilitation app started within 24 hours of acute ischemic stroke with traditional bedside rehabilitation. It enrolls 100 participants (50 per group) at Tri-Service General Hospital and follows them for about one year. Outcomes include upper limb muscle strength, cognitive status, hospital anxiety, and exercise self-efficacy. The study uses randomization to experimental and control groups to assess the added value of early VR rehabilitation in acute care settings.

Why it matters

Potential benefit: If successful, patients may gain greater early improvements in arm strength and cognitive outcomes, with reduced anxiety and higher motivation to participate in rehab.

How similar studies have gone: Previous rehab studies using VR approaches have shown potential benefits, but results vary; this trial adds early, 24-hour initiation in acute care, which is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of acute ischemic stroke with ICD-10 codes: G45-G46.8, I63-I68.8.
* Within 10 days (inclusive) of stroke symptom onset.
* Age 18\~85 years or older.

Exclusion Criteria:

* Comorbid neuromuscular or orthopedic conditions affecting upper limb function.)
* Recurrence of stroke or onset of seizures during the study period.
* Severe visual impairment or visuospatial neglect.
* Inability to cooperate or refusal to participate in the study.

Where it's running

  • Tri Service General Hospital
    Taipei, Taiwan
    Recruiting

Study contacts

  • Principal investigator: Yun Qian Lin — Tri-Service General Hospital (TSGH)
  • Study coordinator: Yun Qian Lin
  • Email: yurilin0709@gmail.com
  • Phone: 28973311

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.