Early VR-Based Rehab for the Arm After Acute Ischemic Stroke
Official title: Effectiveness of Early Intervention With Virtual Reality-based Interactive Rehabilitation on Upper Extremity Muscle Strength, Cognitive Status, Hospital Anxiety and Exercise Self-efficacy in Patients With Acute Ischemic Stroke: A Randomized Controlled Trial
Run by Tri-Service General Hospital (TSGH) · NCT07674329 · Data updated 2026-11-12
This trial tests whether starting virtual reality–based arm rehabilitation within 24 hours of an acute ischemic stroke helps improve arm strength, thinking skills, anxiety, and confidence to exercise compared with standard rehab.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Tri-Service General Hospital (TSGH) Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | March 7, 2025 |
| Main results expected | October 1, 2026 |
| Study ends | October 1, 2026 |
| Registry record updated | June 29, 2026 |
| Trial ID | NCT07674329 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–85 with acute ischemic stroke diagnosed within the past 10 days, able to participate in rehabilitation and without major comorbidities limiting upper-limb function.
✕Probably not a fit
Patients with severe visual impairment, visuospatial neglect, other disabling conditions affecting the upper limb, recurrent strokes, seizures during the study, or inability to cooperate may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares a VR motion-sensing rehabilitation app started within 24 hours of acute ischemic stroke with traditional bedside rehabilitation. It enrolls 100 participants (50 per group) at Tri-Service General Hospital and follows them for about one year. Outcomes include upper limb muscle strength, cognitive status, hospital anxiety, and exercise self-efficacy. The study uses randomization to experimental and control groups to assess the added value of early VR rehabilitation in acute care settings.
Why it matters
Potential benefit: If successful, patients may gain greater early improvements in arm strength and cognitive outcomes, with reduced anxiety and higher motivation to participate in rehab.
How similar studies have gone: Previous rehab studies using VR approaches have shown potential benefits, but results vary; this trial adds early, 24-hour initiation in acute care, which is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of acute ischemic stroke with ICD-10 codes: G45-G46.8, I63-I68.8. * Within 10 days (inclusive) of stroke symptom onset. * Age 18\~85 years or older. Exclusion Criteria: * Comorbid neuromuscular or orthopedic conditions affecting upper limb function.) * Recurrence of stroke or onset of seizures during the study period. * Severe visual impairment or visuospatial neglect. * Inability to cooperate or refusal to participate in the study.
Where it's running
-
Tri Service General Hospital
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Yun Qian Lin — Tri-Service General Hospital (TSGH)
- Study coordinator: Yun Qian Lin
- Email: yurilin0709@gmail.com
- Phone: 28973311
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.