Early gait training to prevent knee cartilage degeneration after ACL surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of early gait training on patients who have undergone anterior cruciate ligament (ACL) reconstruction. It involves a randomized controlled design where one group receives standard rehabilitation while the other group also participates in gait training during the early postoperative period. The study aims to analyze the biomechanical characteristics of gait and the biochemical health of knee cartilage using motion testing and functional MRI. The goal is to provide insights that could guide rehabilitation practices and reduce the risk of cartilage degeneration.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with ACL rupture were diagnosed by MRI;
2. Unilateral ACL rupture for the first time should be performed in our hospital (Department of Sports Medicine, Peking University Third Hospital)The art of reconstruction;
3. Normal BMI range: 18.5-23.9 kg/m2;
4. Within 6 months from the trauma;
5. The affected knee joint has passed the acute stage, no obvious redness, pain,inflammation, and limited joint motion,basically restore joint motion.

Exclusion Criteria:

1. BMI\<18.5 kg/m2 or BMI≥24 kg/m2);
2. There is a history of contralateral lower limb musculoskeletal system injury and surgery;
3. ACL injury time \> 6 months;
4. Outerbridge damage rating Ⅲ and Ⅳ;
5. Patients with meniscal tears who are expected to undergo meniscal suture surgery at the time of ACLR surgery;
6. Serious injury to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament;
7. There is metabolic syndrome (obesity, dyslipidemia, diabetes, etc.), which will involve articular cartilage Epidemic diseases, serious cardiovascular and cerebrovascular diseases, etc.;
8. Those who do not want to accept this treatment

Where it's running

• Peking University Third Hospital
  Beijing, China Recruiting

Study contacts

• Study coordinator: ren shuang, doctor
• Email: xixishuang123@126.com
• Phone: 17610252992

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Visual-guided balance training to improve knee function after ACL reconstruction

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• Predicting knee cartilage wear and pain after early osteoarthritis or a recent ACL injury

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  Recruiting at 2 sites Aalborg University · Aalborg, North Denmark and 1 other locations · NCT07134244

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.