Dual-task Inspiratory Muscle Training for Heart Failure
Official title: Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure
Run by Istanbul University - Cerrahpasa · NCT07581587 · Data updated 2026-11-12
This study tests whether doing breathing muscle training while doing cognitive tasks helps improve thinking, breathing, and daily function in adults with heart failure.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years and up |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Istanbul University - Cerrahpasa Academic / other |
| Locations | 1 site (Istanbul, Fatih) |
| Status | Recruiting |
| Started | July 27, 2026 |
| Main results expected | July 2027 |
| Study ends | December 2027 |
| Registry record updated | July 30, 2026 |
| Trial ID | NCT07581587 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with heart failure with reduced ejection fraction (HFrEF), NYHA class I–III, stable for at least 3 months, MoCA ≥ 21, Turkish literacy, and able to participate.
✕Probably not a fit
Patients with recent major cardiac events, neurological disorders, uncontrolled hypertension/diabetes, or other conditions that prevent participation may receive no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized, single-blind trial, adults with heart failure are assigned to one of three groups: dual-task inspiratory muscle training, standard inspiratory muscle training, or no extra training. Participants train 5 days a week for 8 weeks, with most sessions conducted via telerehabilitation and one supervised session weekly. The study aims to determine if dual-task IMT offers greater benefits for cognitive function, respiratory strength, exercise capacity, and quality of life compared with standard IMT or no intervention. Outcomes include cognitive performance, dyspnea, fatigue, and mood, assessed through standardized measures. The trial targets adults aged 40 and older with HFrEF and stable treatment, and all participants must meet safety and cognitive criteria.
Why it matters
Potential benefit: If successful, dual-task IMT could offer a more effective approach to improve cognition, breathing, and functional status in heart failure patients.
How similar studies have gone: Prior studies show IMT improves respiratory and functional outcomes, but similar dual-task approaches in HF are less established and require testing.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 40 years * Diagnosed with HF with reduced ejection fraction (HFrEF) according to the 2023 ESC HF Guidelines * Classified as NYHA functional class I-III * Clinically stable for at least 3 months and receiving stable pharmacological treatment * Able to read and understand Turkish * MoCA score ≥ 21 * Willingness to participate and provide written informed consent Exclusion Criteria: * Diagnosis of any neurological or neurodegenerative disease (e.g., Parkinson's disease, stroke, dementia, Alzheimer's disease) * Diagnosis of pulmonary disease (e.g., chronic obstructive pulmonary disease, obstructive sleep apnea) * Myocardial infarction within the last 6 months * Uncontrolled hypertension and/or diabetes mellitus * Severe valvular heart disease and/or uncontrolled arrhythmias * Orthopedic, visual, or hearing impairments that may prevent independent test completion * Inability to comply with study procedures or follow instructions
Where it's running
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Istanbul University-Cerrahpaşa, Cardiology Institute
Istanbul, Fatih, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Vildan Fidanoglu, PT, MSc
- Email: fzt.vildanbayraktaroglu@hotmail.com
- Phone: 212-924-24-44
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.