DT-TUG Protocols: Checking if Three Ways to Do the Dual-Task Timed Up and Go Are Reliable

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study compares three dual-task Timed Up and Go protocols to determine their validity and reliability in people with multiple sclerosis. Researchers will assess convergent validity, intra-rater and inter-rater reliability, and calculate measurement error metrics such as SEM and MDC. Bland-Altman plots will be used to visualize agreement between raters. The study uses subtasks of counting backward in threes, verbal fluency, and ball-carrying on a tray to form the dual-task DTUG tests. Participants are adults with MS, 18–65, with EDSS 0–5.5, who do not use walking aids and meet other eligibility criteria, and the lead sponsor is Afyonkarahisar Health Sciences University in collaboration with SANKO University in Gaziantep, Turkey.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Having been diagnosed with MS according to the McDonald criteria revised in 2017,
* Being between the ages of 18 and 65,
* Having an Expanded Disability Status Scale (EDSS) score between 0 and 5.5,
* Not requiring any assistive walking devices.

Exclusion Criteria:

* Pregnancy;
* Having experienced a relapse within the past three months;
* The presence of another neurological condition in addition to MS;
* The presence of a different disorder that could potentially affect gait parameters;
* The presence of visual, auditory, perceptual, or cognitive impairments severe enough to interfere with the test administration

Where it's running

• SANKO University
  Gaziantep, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Emel TAŞVURAN HORATA, PhD — Afyonkarahisar Health Sciences University
• Study coordinator: EMEL TAŞVURAN HORATA, PhD
• Email: ethorata@gmail.com
• Phone: 05547759663

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Treadmill-based virtual reality walking training for MS patients

  This study tests whether a treadmill with virtual reality and smart socks can help people with multiple sclerosis walk better and feel safer in daily life.

  Recruiting Shepherd Center, Atlanta GA · Atlanta, Georgia · NCT07927439

• Virtual Reality and Mental Practice to Improve Balance and Walking in Relapsing MS

  This study tests whether virtual reality training or mental practice can improve balance and walking in people with relapsing–remitting multiple sclerosis.

  Recruiting Cairo University · Giza, Giza Governorate · NCT07918339

• REAL-MS: A Look at Autologous Stem Cell Transplant vs High-Efficacy MS Therapies in Real-World Care

  This study tests how AHSCT compares to high-efficacy MS medicines in adults treated in routine clinical care.

  Recruiting Imperial College London · London and 2 other locations · NCT07899502

• Tolebrutinib in real-world MS care for patients treated by clinicians

  This real-world study sees how tolebrutinib is used for multiple sclerosis patients and what outcomes look like in everyday practice.

  Recruiting Sanofi · Marina, Abu Dhabi Emirate · NCT07898371

• Pilates via live video vs. prerecorded videos for people with multiple sclerosis

  This study tests whether live, coach-led Pilates sessions through video calls are more beneficial than prerecorded Pilates videos for adults with MS.

  Recruiting Yuzuncu Yil University · Van · NCT07893925

• Cooling During Inpatient Rehab for People with MS

  This trial tests whether wearing a cooling vest during intensive training can reduce fatigue and improve walking, strength, balance, and cognition in people with multiple sclerosis during a 3-week inpatient rehab stay.

  Recruiting Klinik Valens · Valens, Canton of St. Gallen · NCT07852156

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.