dPmax test to predict RV failure after LVAD implantation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study analyzes arterial pressure waveform data collected during routine care before and after anesthesia in adults scheduled for LVAD placement. Researchers will compare dPmax measurements with preoperative echo findings and the TAPSE/SPAP ratio to predict right ventricular failure within 30 days after surgery using MCS-ARC criteria. No extra invasive procedures are added for research beyond standard monitoring. The goal is to identify a dPmax threshold that best predicts RV failure and to gauge its predictive performance relative to existing measures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older.
* Scheduled for left ventricular assist device (LVAD) implantation.
* Availability of the clinical data required for the study.
* Willingness and ability to provide informed consent.

Exclusion Criteria:

* Congenital heart disease associated with transposition of the great arteries.
* Ongoing extracorporeal membrane oxygenation (ECMO) or extracorporeal ventricular assist device (ExVAD) support immediately before LVAD implantation.
* Severe aortic regurgitation, severe peripheral arterial disease, or refractory and uncontrolled tachyarrhythmia that may interfere with arterial waveform analysis.
* Unwillingness to participate or cognitive impairment preventing informed consent.

Where it's running

• Ankara Bilkent City Hospital
  Ankara, Çankaya, Turkey (Türkiye) Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pulmonary Embolism Registry from Emergency Care to Long-Term Follow-Up

  This registry follows adults with acute pulmonary embolism to see how care is given in the real world and what happens over time.

  Recruiting at 16 sites Azienda Ospedaliero-Universitaria Careggi · Bagno a Ripoli, Tuscany and 15 other locations · NCT07855679

• Right ventricular–arterial coupling during fluid loading in ICU patients

  This study tests how the right ventricle handles fluid changes in critically ill adults to see how it affects blood flow and congestion.

  Recruiting CHU de Reims · Reims · NCT07537621

• Compare leadless and left bundle branch pacemakers for heart and valve function

  This study tests whether leadless pacemakers or left bundle branch area pacing better preserve heart and tricuspid valve function in adults needing a pacemaker.

  Recruiting Guy's and St Thomas' NHS Foundation Trust · London · NCT07534917

• Right-side heart function after pacemaker, ICD, or CRT implantation

  This project will see if right heart function changes in adults getting a pacemaker, ICD, or CRT by comparing imaging and a blood test before the device and six months later.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, FATIH · NCT07272395

• Feasibility assessment of treatments for right ventricular failure

  This study is testing if adding two different medications to standard care can help people with right heart failure and pulmonary hypertension feel better and if it's possible to do a bigger study in the future.

  Recruiting Phase 2 University of Alberta · Calgary, Alberta and 4 other locations · NCT06570473

• Using valsartan to help treat pulmonary hypertension

  This study is testing if the medication valsartan can help adults with pulmonary arterial hypertension feel better and improve their heart function.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT06053580

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.