Dorsal Root Electrical Stimulation to Help Spasticity in Children with Cerebral Palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial will enroll children with cerebral palsy who are scheduled for selective dorsal rhizotomy. During SDR, researchers will apply higher-frequency dorsal root stimulation alongside the standard clinical test stimulation to see if it reduces the abnormal muscle responses measured by CMAP. The procedure uses a constant current stimulator and the Cadwell Guardian System to deliver stimulation. Outcomes focus on whether the added stimulation can decrease spasticity without altering standard care or insurance coverage. This is a surgical-augmentation approach conducted at a single pediatric center.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children ages 3 to 14
* Diagnosis of Cerebral Palsy
* Require an SDR as determined by the multidisciplinary movement disorders team
* Confirmation that subjects' terms of insurance coverage for their standard of care procedure will not be altered by study enrollment.

Exclusion Criteria:

* No exclusion criteria

Where it's running

• UPMC Children's Hospital of Pittsburgh
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Martin G Piazza, MD — University of Pittsburgh
• Study coordinator: Bailey McDonald, BS
• Email: mcdonaldbm3@upmc.edu
• Phone: 412-692-9966

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gentle spinal stimulation to reduce muscle tightness in children with cerebral palsy

  This will try non-invasive, light spinal cord stimulation with movement tests to see if it reduces spasticity in children ages 5–17 with cerebral palsy.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07516067

• Botulinum toxin A injections to improve movement in children with spastic hemiparesis

  This project will try botulinum toxin type A injections in children aged 8–17 with spastic hemiparesis (GMFCS I–II) to see if their motor function and quality of life improve.

  Recruiting Instituto Teletón Chile · Santiago, Santiago Metropolitan · NCT07034547

• Tracking intellectual and motor development in babies at high risk for cerebral palsy

  This project will follow babies at higher risk for cerebral palsy to see if early thinking and movement signs predict later intellectual and motor outcomes.

  Recruiting at 3 sites University College Cork · Cork and 3 other locations · NCT06857539

• Combining whole body vibration and serial casting for children with cerebral palsy

  This study is testing if combining whole body vibration with special casts and exercises can help children with cerebral palsy move their ankles better and improve their overall mobility.

  Recruiting Nationwide Children's Hospital · Columbus, Ohio · NCT06693388

• Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy

  This study tests whether Sensory Integration Therapy helps improve gross motor function more than standard physical therapy in children aged 4–10 with mixed cerebral palsy.

  Recruiting Riphah International University · Peshawar, Kpk · NCT07921069

• Manual Therapy Before Neuromotor Rehab in Children with Cerebral Palsy

  In this pilot study, researchers test whether 30 minutes of lower-limb manual therapy before functional neuromotor therapy helps improve gait and motor performance in children with spastic cerebral palsy.

  Recruiting LIFE - Research and Care Institute - Santa Lucia IRCCS · Roma, Roma · NCT07902466

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.