Does adding hyperbaric oxygen to a structured exercise program help arthritis-like pains in breast cancer survivors on aromatase inhibitors?
Official title: Addtion of Hyperbaric Oxygen to Programmed Physical Activity in Aromatse Inhibtors-linked Musckoloskeletal Pain in Breast Cancer Patients
Run by Cairo University · NCT07662629 · Data updated 2026-11-12
This study tests whether adding hyperbaric oxygen therapy to a regular exercise program reduces musculoskeletal pain in elderly breast cancer survivors taking aromatase inhibitors.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years to 75 Years |
| Sex | Women only |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Dokki, Giza Governorate) |
| Status | Recruiting |
| Started | May 7, 2026 |
| Main results expected | September 1, 2026 |
| Study ends | September 1, 2026 |
| Registry record updated | June 23, 2026 |
| Trial ID | NCT07662629 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Eligible participants are elderly breast cancer survivors currently using aromatase inhibitors and experiencing musculoskeletal pain.
✕Probably not a fit
Patients without musculoskeletal pain or those not on aromatase inhibitors may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two groups of elderly breast cancer survivors who experience musculoskeletal pain from aromatase inhibitors. Both groups participate in a supervised physical activity program consisting of aerobic training on a treadmill and strengthening exercises three times a week for two months. In addition to exercise, one group receives daily one-hour hyperbaric oxygen therapy five days a week for two months. The study analyzes changes in pain and function to see if the extra hyperbaric treatment provides additional benefit beyond exercise alone.
Why it matters
Potential benefit: If successful, adding hyperbaric oxygen could provide greater reduction in musculoskeletal pain for this patient population.
How similar studies have gone: Prior research on hyperbaric oxygen for cancer treatment-related side effects is mixed; this study explores a novel combination with structured exercise.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * braest cancer survivors * patients receiving aramatase inhibitor drugs * patients with musckolskeletal pains Exclusion Criteria: * cardiac patients * respiratory patients * renal patients
Where it's running
-
Cairo University
Dokki, Giza Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Ali MA Ismail, lecturer — Cairo University
- Study coordinator: Ali MA Ismail, lecturer
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: 01005154209
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.