Clinical trial Recruiting at 1 site Interventional Ages 65 to 75 Women only

Does adding hyperbaric oxygen to a structured exercise program help arthritis-like pains in breast cancer survivors on aromatase inhibitors?

Official title: Addtion of Hyperbaric Oxygen to Programmed Physical Activity in Aromatse Inhibtors-linked Musckoloskeletal Pain in Breast Cancer Patients

Run by Cairo University · NCT07662629 · Data updated 2026-11-12

This study tests whether adding hyperbaric oxygen therapy to a regular exercise program reduces musculoskeletal pain in elderly breast cancer survivors taking aromatase inhibitors.

Quick facts

Study typeInterventional
Ages65 Years to 75 Years
SexWomen only
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Dokki, Giza Governorate)
StatusRecruiting
StartedMay 7, 2026
Main results expectedSeptember 1, 2026
Study endsSeptember 1, 2026
Registry record updatedJune 23, 2026
Trial IDNCT07662629 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Eligible participants are elderly breast cancer survivors currently using aromatase inhibitors and experiencing musculoskeletal pain.

Probably not a fit

Patients without musculoskeletal pain or those not on aromatase inhibitors may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares two groups of elderly breast cancer survivors who experience musculoskeletal pain from aromatase inhibitors. Both groups participate in a supervised physical activity program consisting of aerobic training on a treadmill and strengthening exercises three times a week for two months. In addition to exercise, one group receives daily one-hour hyperbaric oxygen therapy five days a week for two months. The study analyzes changes in pain and function to see if the extra hyperbaric treatment provides additional benefit beyond exercise alone.

Why it matters

Potential benefit: If successful, adding hyperbaric oxygen could provide greater reduction in musculoskeletal pain for this patient population.

How similar studies have gone: Prior research on hyperbaric oxygen for cancer treatment-related side effects is mixed; this study explores a novel combination with structured exercise.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* braest cancer survivors
* patients receiving aramatase inhibitor drugs
* patients with musckolskeletal pains

Exclusion Criteria:

* cardiac patients
* respiratory patients
* renal patients

Where it's running

  • Cairo University
    Dokki, Giza Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.