Diffusion in the growing spine: ADC of the intervertebral disc in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses MRI to measure the apparent diffusion coefficient of the intervertebral disc in children aged 8 to 16. It compares those with idiopathic scoliosis to healthy peers undergoing MRI for routine care. The goal is to characterize diffusion parameters in vivo, without radiation or invasive procedures. The study is conducted at Limoges and Toulouse university hospitals and includes those already scheduled for lumbar or spinal MRI. It is not a treatment trial and does not involve intervention beyond imaging.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age: patients between 8 and 16 years old
* Children undergoing magnetic resonance imaging of the lumbar or spinal region as part of their routine care
* Scoliotic: spinal deformity characterized by a hump on clinical examination and a radiological deformation in the coronal plane greater than 10 ° with no etiology found (idiopathic)
* Healthy: no hump on clinical examination, walking patients (level 1 and 2 of the global motor function classification system)

Exclusion Criteria:

* existence of medullary and vertebral pathology other than scoliosis, history of disc or vertebral infection (spondylo-discitis) on examination, neuro-ectodermal pathology
* behavioral disturbances incompatible with the performance of the magnetic resonance imaging examination.
* Refusal of participation.
* Thoracic scoliosis

Where it's running

• Limoges University Hospital
  Limoges, France Recruiting
• Toulouse University Hospital
  Toulouse, France Not yet recruiting

Study contacts

• Study coordinator: Quentin BALLOUHEY, MD
• Email: quentin.ballouhey@chu-limoges.fr
• Phone: +33555052410

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.