Diet with fermented foods for patients with Ulcerative Colitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of a diet supplemented with fermented foods on inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). The research aims to address the lack of understanding regarding the relationship between diet and intestinal inflammation. Participants will be assigned to either a fermented food-supplemented diet or a regular diet, and their responses will be monitored through various health metrics. The study seeks to provide insights into how dietary modifications can influence inflammatory markers and overall well-being in UC patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Written informed consent
* Male or female subjects, ≥18 years of age
* Confirmed diagnosis of UC
* Symptomatic disease defined as partial Mayo Score 2 to 7 (inclusive)
* Elevated fecal calprotectin

Exclusion Criteria:

* Women who are pregnant, nursing or expect to be pregnant
* Intolerance to fermented food
* Individuals with a body mass index (BMI) lower than 18
* Individuals diagnosed with a serious medical condition (unless approved in writing by a physician)
* Individuals who have been severely weakened by a disease or medical procedure
* Individuals with more than mild-moderate cardiovascular disease or life-threatening cancer (as determined by patient's physician) unless approved by a physician
* Individuals with history of severe cardiac disease (particularly uncompensated congestive heart failure NYHA grade 2 or more or LVEF \< 40%)
* History of relevant intestinal surgery such as total or hemi-colectomy, proctocolectomy, stoma.

Complications of disease such as extraintestinal manifestations (EIMs) are not automatically considered exclusion criteria. Appropriate medical treatment for UC and/or EIMs will not be withheld.

Where it's running

• Stanford University
  Palo Alto, California, United States Recruiting

Study contacts

• Principal investigator: Sidhartha Sinha, MD — Stanford University
• Study coordinator: Touran Fardeen
• Email: tfardeen@stanford.edu
• Phone: 6507367311

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.