Diagnosing vesicoureteric reflux in children using advanced imaging techniques
Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
This study tests if a new imaging technique called CEVUS is better than the traditional method for diagnosing vesicoureteric reflux in young children who have had multiple urinary tract infections.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 0 Years to 6 Years |
| Sex | All |
| Sponsor | Turku University Hospital Government |
| Locations | 1 site (Turku) |
| Trial ID | NCT06138080 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of contrast enhanced voiding ultrasonography (CEVUS) compared to direct isotope cystography for diagnosing vesicoureteric reflux (VUR) in children under six years old. The researchers will recruit 100 pediatric patients who have experienced at least two culture-positive urinary tract infections. Both imaging techniques will be performed on the same day by blinded specialists to ensure unbiased results. The goal is to identify a safer and more accurate method for diagnosing and classifying VUR.
Who should consider this trial
Good fit: Ideal candidates for this study are children under six years old who have had at least two culture-positive urinary tract infections.
Not a fit: Patients with abnormal bladder function or posterior ureteral valves will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy for vesicoureteric reflux in children, minimizing the risks associated with current imaging methods.
How similar studies have performed: While there have been studies on imaging techniques for VUR, this specific comparison of CEVUS and direct isotope cystography is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * under 6 years old patients who have had at least 2 culture positive urinary tract infections Exclusion Criteria: * abnormal bladder function * posterior uretral valves
Where this trial is running
Turku
- Turku University hospital — Turku, Finland (Recruiting)
Study contacts
- Study coordinator: Hanna-Reeta Viljamaa
- Email: hanna-reeta.viljamaa@tyks.fi
- Phone: +35823130000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.