Diagnosing vesicoureteric reflux in children using advanced imaging techniques
Official title: Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
Run by Turku University Hospital · NCT06138080 · Data updated 2026-11-12
This study tests if a new imaging technique called CEVUS is better than the traditional method for diagnosing vesicoureteric reflux in young children who have had multiple urinary tract infections.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 0 Years to 6 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Turku University Hospital Government |
| Locations | 1 site (Turku) |
| Status | Recruiting |
| Started | May 15, 2022 |
| Main results expected | May 15, 2030 |
| Study ends | May 1, 2031 |
| Registry record updated | November 18, 2023 |
| Trial ID | NCT06138080 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children under six years old who have had at least two culture-positive urinary tract infections.
✕Probably not a fit
Patients with abnormal bladder function or posterior ureteral valves will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of contrast enhanced voiding ultrasonography (CEVUS) compared to direct isotope cystography for diagnosing vesicoureteric reflux (VUR) in children under six years old. The researchers will recruit 100 pediatric patients who have experienced at least two culture-positive urinary tract infections. Both imaging techniques will be performed on the same day by blinded specialists to ensure unbiased results. The goal is to identify a safer and more accurate method for diagnosing and classifying VUR.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy for vesicoureteric reflux in children, minimizing the risks associated with current imaging methods.
How similar studies have gone: While there have been studies on imaging techniques for VUR, this specific comparison of CEVUS and direct isotope cystography is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * under 6 years old patients who have had at least 2 culture positive urinary tract infections Exclusion Criteria: * abnormal bladder function * posterior uretral valves
Where it's running
-
Turku University hospital
Turku, Finland Recruiting
Study contacts
- Study coordinator: Hanna-Reeta Viljamaa
- Email: hanna-reeta.viljamaa@tyks.fi
- Phone: +35823130000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.