Changes in activity, sleep, and knee function after same-day discharge knee replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational cohort follows patients undergoing same-day discharge knee arthroplasty (SDD-KA) to characterize changes in activity, sleep quality, knee strength, range of motion, and patient-reported outcomes from before surgery through 12 months after. Wearable accelerometers measure activity and sleep in a preoperative two-week window, during the initial postoperative period through three months, and then for an additional two-week window. The study also compares outcomes between medial unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) as a prespecified secondary analysis. Participants are not randomized; the surgical procedure is determined by clinicians, and the study uses an observational design to explore associations among changes and satisfaction. The setting is Turku University Hospital with collaboration from the UKK Institute, enrolling up to 120 patients (30 UKA, 90 TKA) followed for 12 months postoperatively.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Primary knee osteoarthritis: medial or lateral Kellgren Lawrence grade 3-4 for TKA and antero-medial grade 3-4 for UKA.

Patient criteria for outpatient knee arthroplasty (UKA or TKA):

* Full overnight support by an adult at home after discharge
* At most mild, well-controlled, comorbidities (e.g. hypertension, hypothyroidism, epilepsy, asthma)
* ASA-class 1-2
* Age \<80 years
* BMI \<35 kg/m2

Exclusion Criteria:

* Post-traumatic osteoarthritis
* Neurological disorder aVecting walking or muscle strength
* Inability or unwillingness to use a smartphone or to participate in the study

Exclusion criteria for outpatient surgery:

* History of cardiac or cerebrovascular events
* Conditions affecting consciousness (e.g. syncope of cardiac origin)
* Untreated or central sleep apnoea
* Heart failure
* Diabetes mellitus type 1
* Cognitive impairment or dementia
* History of substance abuse
* Chronic strong opioid therapy or severe pain disorder
* Antithrombotic therapy (e.g. Xarelto, Pradaxa, Plavix or ASA for secondary prevention)
* History of venous thromboembolism or known coagulopathy

Where it's running

• The UKK Institute for Health Promotion Research
  Tampere, Finland Recruiting
• Turku University Hospital
  Turku, Finland Recruiting

Study contacts

• Study coordinator: Matias Hemmilä, Ph.D.
• Email: mmhemm@utu.fi
• Phone: +358440607840

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Custom 3D-printed total ankle and talus replacement for severe bone loss

  This project will try a custom 3D-printed ankle and talus implant to restore function in adults aged 35–75 with severe talar bone loss or compromised ankle bone.

  Recruiting Istituto Ortopedico Rizzoli · Bologna · NCT07569848

• Evaluating wrist and carpal fusion surgeries for pain relief and stability

  This study is testing different wrist surgeries to see if they can help people with chronic pain and instability feel better and regain function after other treatments haven't worked.

  Recruiting at 2 sites Vestre Viken Hospital Trust · Drammen and 1 other locations · NCT06917235

• Using low-dose radiation to treat osteoarthritis

  This study is testing if low-dose radiation therapy can help people with osteoarthritis feel less pain compared to a placebo treatment.

  Recruiting University of Erlangen-Nürnberg Medical School · Erlangen, Bavaria · NCT05887284

• Comparing two techniques for wrist fusion in patients with post-traumatic arthritis

  This study is testing two different surgery techniques for wrist fusion to see which one helps adults with post-traumatic arthritis feel better and regain more movement in their wrists.

  Recruiting at 5 sites University of Alberta · Calgary, Alberta and 4 other locations · NCT04580225

• Post-marketing surveillance of a femoral stem prosthesis for hip replacement

  This study is tracking how well a specific hip replacement device works and its safety in people aged 18 to 75 who are having hip surgery for different joint problems.

  Recruiting at 4 sites Medacta International SA · Vienna and 3 other locations · NCT02748408

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.