Dexamethasone and Bupivacaine in a Shoulder Nerve Block: How It Affects Blood Levels

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind trial compares plasma concentrations of bupivacaine after a single-shot interscalene nerve block when dexamethasone is given perineurally versus intravenously. Adult patients undergoing shoulder surgery with ASA I–II and BMI 20–34 kg/m2 are included, and those with certain medical conditions or allergies are excluded. The study aims to clarify how dexamethasone delivery route influences systemic absorption and potential analgesic effects. The lead sponsor is Pontificia Universidad Catolica de Chile, with sites at Red Salud UCChristus in Santiago.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- ASA I-II patients, with a body mass index (BMI) between 20 and 34 kg/m2 scheduled for shoulder surgery requiring single-needle interscalene block

Exclusion Criteria:

\- Chronic opioid use, liver failure, kidney failure, allergy to protocol drugs

Where it's running

• Red Salud UCChristus
  Santiago, Chile Recruiting

Study contacts

• Study coordinator: Andrea Araneda, MD
• Email: andreaaraneda10@gmail.com
• Phone: 56955043270

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.