Development of a brain atlas for improved treatment of neurological conditions
Physiological Brain Atlas Development
This study is trying to create a detailed brain map to help doctors find the best treatment spots for patients with conditions like Parkinson's, OCD, and epilepsy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 6 Years to 90 Years |
| Sex | All |
| Sponsor | Vanderbilt University Medical Center Academic / other |
| Locations | 1 site (Nashville, Tennessee) |
| Trial ID | NCT00575081 on ClinicalTrials.gov |
What this trial studies
This project aims to create a physiological brain atlas that integrates clinical and physiological data with anatomical MRI locations. It focuses on patients undergoing stereotactic brain procedures for conditions such as Parkinson's Disease, OCD, Dystonia, Essential Tremor, and Epilepsy. By utilizing advanced MRI normalization algorithms, the atlas will help clinicians predict optimal treatment locations and improve patient outcomes through data analysis. The collected data will be stored securely in a HIPAA-compliant manner, ensuring patient confidentiality while facilitating research and clinical applications.
Who should consider this trial
Good fit: Ideal candidates include patients aged 6 to 90 who are recommended for or have consented to undergo stereotactic brain procedures.
Not a fit: Patients who are not recommended for stereotactic brain procedures or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this atlas could lead to more precise and effective treatments for various neurological disorders.
How similar studies have performed: Other studies have shown promise in using similar approaches to improve treatment outcomes in neurological conditions, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who are recommended for Stereotactic Brain procedures * Any patient who has agreed to undergo a Stereotactic Brain procedure * Patients age under 6 -90 years old Exclusion Criteria: * Patients who fail recommendation for Stereotactic Brain procedures * Patients not consented for Stereotactic Brain procedures * Patients outside the age range of 6 -90 years old * Patients or legal guardians not able to provide informed consent
Where this trial is running
Nashville, Tennessee
- Vanderbilt Univeristy — Nashville, Tennessee, United States (Recruiting)
Study contacts
- Principal investigator: Darioq j Englot, MD, Ph.D. — Vanderbilt University, Dept. Neurosurgery
- Study coordinator: Dario J Englot, MD, Ph.D.
- Email: dario.englot@vumc.org
- Phone: 615-322-7417
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.