Clinical trial Recruiting at 1 site Observational Ages 6 to 90

Development of a brain atlas for improved treatment of neurological conditions

Official title: Physiological Brain Atlas Development

Run by Vanderbilt University Medical Center · NCT00575081 · Data updated 2026-11-12

This study is trying to create a detailed brain map to help doctors find the best treatment spots for patients with conditions like Parkinson's, OCD, and epilepsy.

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Quick facts

Study typeObservational
Ages6 Years to 90 Years
SexAll
Enrollment5000 (estimated)
SponsorVanderbilt University Medical Center
Academic / other
Locations1 site (Nashville, Tennessee)
StatusRecruiting
StartedAugust 2006
Main results expectedAugust 2027
Study endsAugust 2027
Registry record updatedAugust 26, 2026
Trial IDNCT00575081 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients aged 6 to 90 who are recommended for or have consented to undergo stereotactic brain procedures.

Probably not a fit

Patients who are not recommended for stereotactic brain procedures or those unable to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to create a physiological brain atlas that integrates clinical and physiological data with anatomical MRI locations. It focuses on patients undergoing stereotactic brain procedures for conditions such as Parkinson's Disease, OCD, Dystonia, Essential Tremor, and Epilepsy. By utilizing advanced MRI normalization algorithms, the atlas will help clinicians predict optimal treatment locations and improve patient outcomes through data analysis. The collected data will be stored securely in a HIPAA-compliant manner, ensuring patient confidentiality while facilitating research and clinical applications.

Why it matters

Potential benefit: If successful, this atlas could lead to more precise and effective treatments for various neurological disorders.

How similar studies have gone: Other studies have shown promise in using similar approaches to improve treatment outcomes in neurological conditions, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients who are recommended for Stereotactic Brain procedures
* Any patient who has agreed to undergo a Stereotactic Brain procedure
* Patients age under 6 -90 years old

Exclusion Criteria:

* Patients who fail recommendation for Stereotactic Brain procedures
* Patients not consented for Stereotactic Brain procedures
* Patients outside the age range of 6 -90 years old
* Patients or legal guardians not able to provide informed consent

Where it's running

  • Vanderbilt Univeristy
    Nashville, Tennessee, United States
    Recruiting

Study contacts

  • Principal investigator: Darioq j Englot, MD, Ph.D. — Vanderbilt University, Dept. Neurosurgery
  • Study coordinator: Dario J Englot, MD, Ph.D.
  • Email: dario.englot@vumc.org
  • Phone: 615-322-7417

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.