Developing a tool to assess fluid status in patients with acute kidney injury

A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney Injury

Observational University of Hertfordshire · NCT05538351

This study is testing a new tool to help doctors better understand fluid levels in patients with acute kidney injury to improve their care.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Hertfordshire Academic / other
Locations1 site (Stevenage)
Trial IDNCT05538351 on ClinicalTrials.gov

What this trial studies

This study focuses on developing an Enhanced Fluid Assessment Tool specifically for patients experiencing Acute Kidney Injury (AKI). It involves identifying effective methods for assessing fluid status, including bioimpedance and patient-reported symptoms. The study is divided into three workstreams: the first identifies useful assessment techniques, the second ranks these techniques to create the tool, and the third evaluates the tool's practicality in clinical settings. The goal is to standardize fluid assessment to improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adult patients over 18 years old who are diagnosed with acute kidney injury within 72 hours of hospital admission.

Not a fit: Patients requiring dialysis, those receiving end-of-life care, or individuals with certain medical conditions like acute coronary syndrome will not benefit from this study.

Why it matters

Potential benefit: If successful, this tool could lead to more accurate fluid management in patients with AKI, potentially reducing kidney damage and improving recovery.

How similar studies have performed: While the approach to developing a standardized fluid assessment tool is innovative, similar studies have shown the importance of accurate fluid management in AKI, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Workstream 1 and 3 (phase 3):

Patients who will be included in the study will be Adult patients (over 18 years old) identified as having an acute kidney injury (AKI) within 72 hours of admission to hospital.

Workstream 2:

Experts in fluid assessment (Doctors, Nurses and AHPs). Persons included will be experts in their field of practice and have a recognised expertise in fluid assessment.

Workstream 3:

Phase 1: Experts in fluid assessment (Doctors, Nurses and AHPs). Phase 2: Staff nurses currently working on a clinical ward.

Exclusion Criteria:

* Patients who have kidney failure requiring dialysis or who are being conservatively managed.
* Patients who are receiving end of Life (EoL) care.
* Patients who have a pacemaker as this interferes with bioimpedance (WS1+3).
* There is no baseline creatinine.
* The patient has acquired an AKI 72 hours after admission to hospital.
* The patient has acute coronary syndrome

Where this trial is running

Stevenage

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Kidney Injurydehydrationhypotensionhypovolaemiarespiratory rateextracellular fluidhypertensionbody weight changes
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.