Developing a model to predict risks of iodine contrast medium extravasation

Development and Validation of a Risk Prediction Model for Iodinated Contrast Medium Extravasation in Patients Undergoing Contrast-enhanced Computed Tomography

Observational Tongji Hospital · NCT06859242

This study is trying to create a tool to help doctors predict which patients might have problems with iodine contrast during CT scans, so they can manage the risks better.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
SexAll
SponsorTongji Hospital Academic / other
Drugs / interventionschemotherapy
Locations1 site (Wuhan, Hubei)
Trial IDNCT06859242 on ClinicalTrials.gov

What this trial studies

This observational study aims to create a risk prediction model for iodine contrast agent extravasation during enhanced CT examinations. It employs a retrospective case-control design, comparing patients who experienced extravasation with those who did not. Data collected includes demographic information, medical history, examination parameters, venous access details, and environmental factors. The goal is to implement this model clinically to enhance risk management for iodine contrast agent extravasation.

Who should consider this trial

Good fit: Ideal candidates for this study are patients undergoing enhanced CT examinations who are willing to participate and do not have contraindications to iodine contrast.

Not a fit: Patients with iodine contrast allergies, hyperthyroidism, or those in critical condition may not benefit from this study.

Why it matters

Potential benefit: If successful, this model could significantly reduce the incidence of iodine contrast medium extravasation and improve patient safety during CT examinations.

How similar studies have performed: While similar predictive models have been explored, this specific approach to iodine contrast extravasation is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Volunteer to participate in this study.
2. Without contraindications such as iodine contrast allergy or hyperthyroidism. -

Exclusion Criteria:

1. There are communication barriers between researchers and patients.
2. Due to critical condition or unstable vital signs, patients should be transferred to relevant clinical departments for treatment or observation immediately after examination.

Where this trial is running

Wuhan, Hubei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Extravasation of Contrast MediaPredictive ModelsMachineRisk Management
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.