Determinants of Physical Frailty in Parkinson’s Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cross‑sectional observational study will examine associations among motor imagery capacity, interoceptive awareness, kinesiophobia, physical activity level, symptom severity, and physical frailty in adults with Parkinson’s disease. Participants will complete questionnaires and undergo functional assessments to explore these biopsychosocial factors. The findings aim to provide insight into factors linked with frailty and potential targets for intervention in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinically diagnosed Parkinson's disease
* Hoehn and Yahr stage 1-3
* Age 40 to 85 years
* Mini-Mental State Examination (MMSE) score ≥24
* Attending the Movement Disorders Outpatient Clinic, Department of Neurology
* Able to understand the study procedures and provide written informed consent

Exclusion Criteria:

* Major depressive disorder or psychotic disorder
* Advanced dementia
* Severe cardiovascular or respiratory disease
* Uncontrolled chronic systemic disease (e.g., diabetes mellitus or hypertension)
* Additional neurological or orthopedic conditions that may affect assessment performance
* Severe visual or hearing impairment that could interfere with study assessments
* Inability to cooperate with the physiotherapist during study assessments

Where it's running

• Acibadem University
  Istanbul, Turkey, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Nuray ALACA
• Email: nuray.alaca@acibadem.edu.tr
• Phone: 05324251290

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• One-day exercise test to see how brain and body react in epilepsy, cognitive disorders, Parkinson's, dementia, and related conditions

  A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT07883720

• Tributyrin for PSP: a virtual, early-phase study

  This study tests whether tributyrin is safe and tolerable in people with Progressive Supranuclear Palsy who are 45 or older, using virtual visits.

  Recruiting Phase 1/2 University of Michigan · Ann Arbor, Michigan · NCT07863180

• A look at why Lewy body conditions cause visual hallucinations

  This study tests brain‑imaging in people with Lewy body diseases who do or don’t experience visual hallucinations, and in healthy volunteers, to see how brain networks might create these images.

  Recruiting NYU Langone Health · New York, New York · NCT07849413

• How physical activity might help people with Parkinson’s disease who have DBS-STN implants

  This study tests whether adding regular physical activity can help people with Parkinson’s who have DBS-STN stimulation by trying a structured physiotherapy approach alongside standard care.

  Recruiting Medical University of Warsaw · Warsaw · NCT07838636

• Can hippotherapy improve mobility, gait, balance, and quality of life in people with Parkinson's disease?

  This pilot trial tests whether adding horse-assisted therapy to standard rehab helps mobility, gait, balance, and perceived health in adults with Parkinson's disease.

  Recruiting Klinik Valens · Valens, Canton of St. Gallen · NCT07802509

• Gut methane and Parkinson's: measuring if a probiotic helps people with Parkinson's, REM sleep behavior disorder, or cognitive concerns

  This study tests whether a probiotic containing Limosilactobacillus reuteri can help people with Parkinson's disease, those at high risk for PD, and related cognitive issues by potentially improving gut methane levels and overall symptoms.

  Recruiting University of Cambridge · Cambridge, CB2 · NCT07786116

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.