Detecting spinal cord lesions in inflammatory diseases using advanced MRI techniques
Official title: Detection of Spinal Cord Lesions Using the MP2RAGE Sequence in Inflammatory Diseases of the Neuraxis
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT06589999 · Data updated 2026-11-12
This study is testing a new MRI technique to see if it can help find small spinal cord lesions in people with inflammatory diseases like multiple sclerosis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 196 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | July 31, 2024 |
| Main results expected | July 2026 |
| Study ends | July 2026 |
| Registry record updated | January 5, 2026 |
| Trial ID | NCT06589999 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who are scheduled for an MRI of the spinal cord due to inflammatory neuraxial disease.
✕Probably not a fit
Patients who are pregnant or have contraindications to MRI will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to improve the detection of spinal cord lesions in patients with inflammatory diseases, particularly multiple sclerosis, by utilizing the MP2RAGE MRI sequence. The study focuses on the cervical segments of the spinal cord, where lesions are often small and difficult to visualize with standard MRI protocols. By implementing standardized acquisition protocols, the study seeks to enhance the sensitivity and specificity of spinal cord lesion detection, which is crucial for accurate diagnosis and management of multiple sclerosis. Participants will undergo MRI scans as part of their routine clinical assessment.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses of multiple sclerosis, allowing for timely and appropriate treatment interventions.
How similar studies have gone: Other studies have shown promising results with advanced MRI techniques for detecting spinal cord lesions, indicating that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient aged over 18 years * scheduled to undergo 1.5T or 3T MRI of the spinal cord as part of an initial assessment or reassessment of inflammatory neuraxial disease. * Express consent to participate in the study * Member or beneficiary of a social security scheme Exclusion Criteria: * Patient benefiting from a legal protection measure * Pregnant women * Absolute or relative contraindication to 1.5T or 3T MRI
Where it's running
-
Hopital Fondation Adolphe de Rothschild
Paris, France Recruiting
Study contacts
- Study coordinator: Yavchitz
- Email: ayavchitz@for.paris
- Phone: 33 + 148036454
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.