Clinical trial Recruiting at 1 site Observational Ages 18 and up

Detecting spinal cord lesions in inflammatory diseases using advanced MRI techniques

Official title: Detection of Spinal Cord Lesions Using the MP2RAGE Sequence in Inflammatory Diseases of the Neuraxis

Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT06589999 · Data updated 2026-11-12

This study is testing a new MRI technique to see if it can help find small spinal cord lesions in people with inflammatory diseases like multiple sclerosis.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment196 (estimated)
SponsorFondation Ophtalmologique Adolphe de Rothschild
Research network
Locations1 site (Paris)
StatusRecruiting
StartedJuly 31, 2024
Main results expectedJuly 2026
Study endsJuly 2026
Registry record updatedJanuary 5, 2026
Trial IDNCT06589999 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old who are scheduled for an MRI of the spinal cord due to inflammatory neuraxial disease.

Probably not a fit

Patients who are pregnant or have contraindications to MRI will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to improve the detection of spinal cord lesions in patients with inflammatory diseases, particularly multiple sclerosis, by utilizing the MP2RAGE MRI sequence. The study focuses on the cervical segments of the spinal cord, where lesions are often small and difficult to visualize with standard MRI protocols. By implementing standardized acquisition protocols, the study seeks to enhance the sensitivity and specificity of spinal cord lesion detection, which is crucial for accurate diagnosis and management of multiple sclerosis. Participants will undergo MRI scans as part of their routine clinical assessment.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses of multiple sclerosis, allowing for timely and appropriate treatment interventions.

How similar studies have gone: Other studies have shown promising results with advanced MRI techniques for detecting spinal cord lesions, indicating that this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient aged over 18 years
* scheduled to undergo 1.5T or 3T MRI of the spinal cord as part of an initial assessment or reassessment of inflammatory neuraxial disease.
* Express consent to participate in the study
* Member or beneficiary of a social security scheme

Exclusion Criteria:

* Patient benefiting from a legal protection measure
* Pregnant women
* Absolute or relative contraindication to 1.5T or 3T MRI

Where it's running

  • Hopital Fondation Adolphe de Rothschild
    Paris, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.