Decoding brain signals for motor control in epilepsy patients
Official title: Decoding of Neuronal Potentials Associated With Motor Performance and Motor Imagery Obtained Using Intracranial stereoEEG Electrodes
Run by Research Center of Neurology, Russia · NCT06432907 · Data updated 2026-11-12
This study is testing a brain-computer interface to see if it can help people with drug-resistant epilepsy control their hand movements using brain signals.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Research Center of Neurology, Russia Government |
| Locations | 1 site (Moscow) |
| Status | Recruiting |
| Started | June 6, 2024 |
| Main results expected | December 25, 2026 |
| Study ends | December 25, 2026 |
| Registry record updated | July 24, 2025 |
| Trial ID | NCT06432907 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 70 with stereoEEG electrodes implanted for medical reasons and who can provide informed consent.
✕Probably not a fit
Patients with cognitive impairments, severe visual impairments, or upper limb motor disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the accuracy of a brain-computer interface (BCI) using stereoEEG signals in patients with drug-resistant epilepsy. Participants, who already have stereoEEG electrodes implanted for clinical reasons, will engage in motor tasks to record neuronal signals associated with hand movement and motor imagery. The study will last no more than 60 minutes per participant, focusing on non-epileptogenic tasks to ensure safety during the recording process. The data collected will contribute to understanding BCI capabilities in controlling motor functions.
Why it matters
Potential benefit: If successful, this study could enhance the development of brain-computer interfaces that improve motor control for patients with neurological conditions.
How similar studies have gone: Other studies have shown promise in using brain-computer interfaces for motor control, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * male and female patients who have had stereoEEG electrodes implanted for medical reasons; * voluntary informed consent to participate in the study; * age from 18 to 70 years. Exclusion Criteria: * patient refusal to participate in the study; * cognitive impairment that prevents following the study instructions; * severe visual impairment that does not allow viewing visual instructions on a computer screen; * upper limb paresis or other motor disorders; * pain in the hand of any etiology; * any acute diseases, exacerbation of chronic diseases, acute life-threatening conditions; * occurrence of an epileptic attack during the experiment.
Where it's running
-
Research center of neurology, Department of neurorehabilitation and physiotherapy
Moscow, Russia Recruiting
Study contacts
- Study coordinator: Olesya A Mokienko, MD PhD
- Email: lesya.md@yandex.ru
- Phone: +74953747776
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Modified ketogenic diet for adults with drug-resistant epilepsy
This study tests whether a modified ketogenic diet can help adults with drug-resistant epilepsy see fewer seizures and feel better overall.
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Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy
This study tests whether low intensity focused ultrasound can help reduce seizures in adults with drug‑resistant epilepsy.
-
iVEAcare Neuromodulation System for drug‑resistant epilepsy: a feasibility look
This study tests whether the iVEAcare neuromodulation system is safe and can help reduce seizures and improve quality of life in people with drug‑resistant epilepsy.
-
Real-world use of the OneRF Ablation System for epilepsy
This registry collects real-world outcomes and device performance from patients with drug-resistant epilepsy who are treated with SEEG-guided RF ablation using the OneRF system.
-
Overnight Temporal Interference Stimulation for Temporal Lobe Epilepsy
This study tests whether overnight, non-invasive temporal interference stimulation to the hippocampus can reduce seizure-related brain activity and improve sleep in adults with drug-resistant temporal lobe epilepsy.
-
Biomarkers of Response to SEEG Thermocoagulation
This study tests biomarkers to see if they predict how well SEEG-guided radiofrequency thermocoagulation helps people with drug-resistant focal epilepsy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.