Decoding brain signals for motor control in epilepsy patients
Decoding of Neuronal Potentials Associated With Motor Performance and Motor Imagery Obtained Using Intracranial stereoEEG Electrodes
This study is testing a brain-computer interface to see if it can help people with drug-resistant epilepsy control their hand movements using brain signals.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Research Center of Neurology, Russia Government |
| Locations | 1 site (Moscow) |
| Trial ID | NCT06432907 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the accuracy of a brain-computer interface (BCI) using stereoEEG signals in patients with drug-resistant epilepsy. Participants, who already have stereoEEG electrodes implanted for clinical reasons, will engage in motor tasks to record neuronal signals associated with hand movement and motor imagery. The study will last no more than 60 minutes per participant, focusing on non-epileptogenic tasks to ensure safety during the recording process. The data collected will contribute to understanding BCI capabilities in controlling motor functions.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 70 with stereoEEG electrodes implanted for medical reasons and who can provide informed consent.
Not a fit: Patients with cognitive impairments, severe visual impairments, or upper limb motor disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the development of brain-computer interfaces that improve motor control for patients with neurological conditions.
How similar studies have performed: Other studies have shown promise in using brain-computer interfaces for motor control, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * male and female patients who have had stereoEEG electrodes implanted for medical reasons; * voluntary informed consent to participate in the study; * age from 18 to 70 years. Exclusion Criteria: * patient refusal to participate in the study; * cognitive impairment that prevents following the study instructions; * severe visual impairment that does not allow viewing visual instructions on a computer screen; * upper limb paresis or other motor disorders; * pain in the hand of any etiology; * any acute diseases, exacerbation of chronic diseases, acute life-threatening conditions; * occurrence of an epileptic attack during the experiment.
Where this trial is running
Moscow
- Research center of neurology, Department of neurorehabilitation and physiotherapy — Moscow, Russia (Recruiting)
Study contacts
- Study coordinator: Olesya A Mokienko, MD PhD
- Email: lesya.md@yandex.ru
- Phone: +74953747776
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.