Cyanoacrylate glue versus collagen sponge for healing palatal donor wounds

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center interventional Early Phase 1 trial at Beirut Arab University compares cyanoacrylate tissue adhesive (PeriAcryl) to a collagen sponge for managing palatal donor wounds after free gingival graft harvesting. Eligible healthy adult patients are assigned to either PeriAcryl applied over the wound or a collagen sponge stabilized with sutures, then followed at scheduled visits to monitor healing and complications. Primary outcomes are wound healing and re-epithelialization, while secondary outcomes include patient satisfaction and oral-health–related quality of life. Clinical exams and patient-reported measures will document healing speed, postoperative symptoms, and any adverse events.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Low-moderate anesthetic risk (ASA I-II)
* No restriction on ethnicity or gender
* Patients requiring FGG from the palate for periodontal plastic surgery
* Clinically healthy gingiva after phase I therapy
* Full-mouth plaque index grades 0 and 1
* Bleeding scores \<15%

Exclusion Criteria:

* Patients who smoke \> 10 cigarettes/day
* Patients with coagulation disorders
* Systemic diseases
* Patients on certain medications that may affect periodontal tissues
* Pregnant and lactating patient
* Patients with allergies to drugs that will be prescribed during the treatment phase
* Pathological mental conditions (dementia, psychosis) and lack of cooperation
* Excessive gag reflex

Where it's running

• Beirut Arab University
  Beirut, Lebanon Recruiting

Study contacts

• Study coordinator: Dania EL Rostom, MSc Oral and Dental Surgery
• Email: daniarostom1999@hotmail.com
• Phone: +96171659355

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.