Customized video to reduce anxiety for brain tumor patients and caregivers during radiation treatment

Novel Intervention to Reduce Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors With a Customized Neuro-Imaging Referenced Symptom Video

Not applicable Interventional M.D. Anderson Cancer Center · NCT04479696

This study tests if a personalized video can help reduce anxiety for brain tumor patients and their caregivers during radiation treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment117 (estimated)
Ages18 Years and up
SexAll
SponsorM.D. Anderson Cancer Center Academic / other
Drugs / interventionsradiation
Locations1 site (Houston, Texas)
Trial IDNCT04479696 on ClinicalTrials.gov

What this trial studies

This trial investigates whether a customized neuro-imaging referenced symptom video can alleviate anxiety in patients with newly diagnosed brain tumors and their caregivers undergoing radiation treatment. Participants are randomized into two groups: one receiving standard care information and the other receiving the customized video intervention. The study aims to assess the impact of the video on anxiety levels during and after radiation, as well as its effects on quality of life and distress. The intervention is designed to provide tailored information about the patient's specific tumor and treatment-related symptoms.

Who should consider this trial

Good fit: Ideal candidates include adult patients with newly diagnosed gliomas (WHO grade 2-4) who are scheduled for a 6-week course of radiotherapy after surgery.

Not a fit: Patients with significant cognitive or psychiatric symptoms that hinder their ability to complete questionnaires may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce anxiety and improve the quality of life for brain tumor patients and their caregivers during a challenging treatment process.

How similar studies have performed: Other studies have shown promising results using educational interventions to reduce anxiety in cancer patients, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PATIENT ELIGIBILITY CRITERIA: Adult patients with newly diagnosed glioma (World Health Organization \[WHO\] grade 2-4) who are planned for a 6-week course of radiotherapy after surgery
* PATIENT ELIGIBILITY CRITERIA: Able to complete questionnaires in English
* PATIENT ELIGIBILITY CRITERIA: Has a post-operative diagnostic magnetic resonance imaging (MRI) of the brain with and without contrast acquired within 4 weeks of the start of radiotherapy
* CAREGIVER ELIGIBILITY CRITERIA: Adult caregiver (\>= 18 years) who is accompanying an eligible patient consented to the study
* CAREGIVER ELIGIBILITY CRITERIA: The patient who the caregiver is accompanying is consented for participation on the study
* CAREGIVER ELIGIBILITY CRITERIA: Able and willing to complete questionnaires in English

Exclusion Criteria:

* PATIENT ELIGIBILITY CRITERIA: Significant cognitive or psychiatric symptoms that prevent the ability to complete the questionnaires as determined by the assessing staff in the pre-intervention evaluation
* PATIENT ELIGIBILITY CRITERIA: Poor performance status (Karnofsky performance status \[KPS\] \< 60) that prevent the ability to complete the questionnaires
* CAREGIVER ELIGIBILITY CRITERIA: Significant cognitive or psychiatric symptoms that prevent the ability to complete the questionnaires as determined by the assessing staff in the pre-intervention evaluation

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions GlioblastomaWHO Grade II GliomaWHO Grade III Glioma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.