Customized video to reduce anxiety for brain tumor patients and caregivers during radiation treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates whether a customized neuro-imaging referenced symptom video can alleviate anxiety in patients with newly diagnosed brain tumors and their caregivers undergoing radiation treatment. Participants are randomized into two groups: one receiving standard care information and the other receiving the customized video intervention. The study aims to assess the impact of the video on anxiety levels during and after radiation, as well as its effects on quality of life and distress. The intervention is designed to provide tailored information about the patient's specific tumor and treatment-related symptoms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* PATIENT ELIGIBILITY CRITERIA: Adult patients with newly diagnosed glioma (World Health Organization \[WHO\] grade 2-4) who are planned for a 6-week course of radiotherapy after surgery
* PATIENT ELIGIBILITY CRITERIA: Able to complete questionnaires in English
* PATIENT ELIGIBILITY CRITERIA: Has a post-operative diagnostic magnetic resonance imaging (MRI) of the brain with and without contrast acquired within 4 weeks of the start of radiotherapy
* CAREGIVER ELIGIBILITY CRITERIA: Adult caregiver (\>= 18 years) who is accompanying an eligible patient consented to the study
* CAREGIVER ELIGIBILITY CRITERIA: The patient who the caregiver is accompanying is consented for participation on the study
* CAREGIVER ELIGIBILITY CRITERIA: Able and willing to complete questionnaires in English

Exclusion Criteria:

* PATIENT ELIGIBILITY CRITERIA: Significant cognitive or psychiatric symptoms that prevent the ability to complete the questionnaires as determined by the assessing staff in the pre-intervention evaluation
* PATIENT ELIGIBILITY CRITERIA: Poor performance status (Karnofsky performance status \[KPS\] \< 60) that prevent the ability to complete the questionnaires
* CAREGIVER ELIGIBILITY CRITERIA: Significant cognitive or psychiatric symptoms that prevent the ability to complete the questionnaires as determined by the assessing staff in the pre-intervention evaluation

Where it's running

• M D Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Caroline Chung — M.D. Anderson Cancer Center
• Study coordinator: Caroline Chung
• Email: cchung3@mdanderson.org
• Phone: 713-745-5422

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Chemotherapy and radiation therapy for treating certain types of gliomas

  This study is testing if a combination of a chemotherapy drug and radiation therapy can help people with certain types of brain tumors live longer and feel better.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04623931

• Lorlatinib for newly diagnosed high-grade glioma with ALK or ROS1 fusions

  This trial will test whether the oral medicine lorlatinib helps children and young adults (ages 1–21) with newly diagnosed high-grade gliomas that have ALK or ROS1 fusions, given alone, with chemotherapy, or after radiation.

  Recruiting at 2 sites Early Phase 1 Nationwide Children's Hospital · Aurora, Colorado and 17 other locations · NCT06333899

• Combining ribociclib and everolimus for treating high-grade gliomas in young patients

  This study is testing if a combination of two drugs, ribociclib and everolimus, can help young patients with high-grade gliomas live longer and feel better after their initial treatment.

  Recruiting at 12 sites Phase 2 Nationwide Children's Hospital · Aurora, Colorado and 19 other locations · NCT05843253

• Genetic profiling for pediatric high-grade glioma treatment eligibility

  This study is testing if genetic testing of brain tumors in children and young adults with high-grade gliomas can help match them to the best treatment options.

  Recruiting at 13 sites Nationwide Children's Hospital · Aurora, Colorado and 21 other locations · NCT05839379

• Using advanced MRI techniques to evaluate lower grade gliomas

  This study is testing if advanced MRI techniques can help doctors better understand and track the growth of lower grade brain tumors in patients.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT04540107

• YN003 injection in glioma patients

  This phase 1 study tests whether YN003 injected IV is safe and tolerable for adults with recurrent or progressive glioma, and to explore how the drug behaves in the body and any early signs of activity.

  Recruiting at 2 sites Phase 1 Beijing Inno Medicine Co., Ltd. · Los Angeles, California and 4 other locations · NCT07929909

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.