Customized PEEK Membranes vs PTFE Membranes for Maxillary Ridge Augmentation
Official title: Custom-Made Polyether Ether Ketone Membrane Versus Polytetrafluoroethylene Membrane in Maxillary Alveolar Ridge Augmentation: A Randomized Controlled Clinical Trial
Run by Mansoura University · NCT07679451 · Data updated 2026-11-12
This study tests whether a patient-specific 3D-printed PEEK membrane works better than a standard PTFE membrane to help build up the upper jaw ridge before dental implants.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 45 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Mansoura University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Al Mansurah, Dakhaliya) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | January 1, 2027 |
| Study ends | February 1, 2027 |
| Registry record updated | July 1, 2026 |
| Trial ID | NCT07679451 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20-45 with vertical, horizontal, or combined maxillary alveolar defects in the esthetic zone requiring ridge augmentation before implants.
✕Probably not a fit
Patients with uncontrolled medical conditions, active smoking, prior radiotherapy or chemotherapy, or bisphosphonate use may not benefit and could be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized trial, patients needing maxillary ridge augmentation in the esthetic zone are assigned to receive either a custom 3D-printed PEEK membrane or a PTFE membrane during guided bone regeneration. Both groups use autogenous bone grafts with xenogeneic substitutes, and membranes are secured with appropriate methods. Outcomes are measured with clinical assessments and CBCT scans immediately after surgery, at 6 months, and at 12 months to evaluate bone gain and soft tissue healing, as well as complication rates. The study aims to determine differences in volumetric, horizontal, and vertical bone regeneration between the two membrane types. Recruitment will occur at Mansoura University with 30 participants randomized equally into two groups.
Why it matters
Potential benefit: If successful, patients may experience better bone regeneration and soft tissue healing, potentially improving implant outcomes.
How similar studies have gone: Prior GBR studies have shown that membrane choice can influence healing, but this exact comparison between customized PEEK and PTFE membranes is relatively novel and under exploration.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age between 20 and 45 years. Male or female participants. Presence of single or multiple missing teeth associated with vertical alveolar defects (vertical bone height less than 8 mm), horizontal alveolar defects (ridge width less than 6 mm), or combined defects in the maxillary esthetic zone requiring alveolar ridge augmentation before implant placement. Good oral hygiene. Exclusion Criteria: Uncontrolled medical disorders contraindicating surgical intervention. Systemic diseases or medications affecting bone metabolism. Current or previous bisphosphonate therapy. History of radiotherapy. History of chemotherapy. Smokers.
Where it's running
-
Dania Raad
Al Mansurah, Dakhaliya, Egypt Recruiting
Study contacts
- Study coordinator: Dania Raad, BDS
- Email: raaddania7@gmail.com
- Phone: 00201063498933
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.