Culturally adapted harm reduction intervention for Black adults misusing opioids and stimulants

Culturally AdapTed Harm Reduction Intervention: Community Engaged InterVention for Black Adults That MisusE Opioids and Stimulants

Not applicable Interventional University of Kentucky · NCT06609278

This study is testing a new support program designed for Black adults who misuse opioids and stimulants to see if it helps them better understand and use tools for preventing overdoses.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Kentucky Academic / other
Locations3 sites (Louisville, Kentucky and 2 other locations)
Trial IDNCT06609278 on ClinicalTrials.gov

What this trial studies

This study aims to develop and test a culturally adapted harm reduction intervention specifically for Black adults who misuse opioids and/or stimulants. It employs a mixed methods approach, beginning with qualitative focus groups to gather insights from participants about their experiences and needs related to overdose prevention. Following this, the intervention will be piloted to assess its effectiveness in increasing knowledge and confidence in using harm reduction strategies, such as Narcan and Fentanyl Test Strips. The study will take place in Louisville, KY, and Cincinnati, OH, focusing on participants who have misused substances in the past six months.

Who should consider this trial

Good fit: Ideal candidates for this study are Black adults residing in Louisville, KY, or Cincinnati, OH, who have reported misuse of opioids and/or stimulants in the last six months.

Not a fit: Patients who do not identify as Black or African American, or those who have previously participated in the study's Aim 1, may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance the knowledge and skills of Black adults in overdose prevention and harm reduction techniques.

How similar studies have performed: While this approach is tailored specifically for Black adults, similar harm reduction interventions have shown promise in other populations, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Identify as Black or African American
* Currently a resident of study areas
* Report misuse of stimulants and/or opioids in the last six months

Exclusion Criteria:

* Do not identify as Black or African American
* If they participated in Aim 1 of the study
* Do not want to be audio-recorded

Where this trial is running

Louisville, Kentucky and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid UseStimulant UseHarm ReductionOpioid OverdoseStimulant MisuseOpioid MisuseNarcanFentanyl Test Strips
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.