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Creating a national database for patients with parathyroid cancer and atypical adenoma in Italy

Creation, Management and Analysis of a National Database of Patients with Parathyroid Carcinoma or Atypical Parathyroid Adenoma

Observational F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore · NCT06645951

This study is creating a national database to collect information about patients with parathyroid cancer and atypical adenoma in Italy to help improve their treatment and care.

Quick facts

Study typeObservational
Enrollment300 (estimated)
SexAll
SponsorF.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore Academic / other
Locations33 sites (Bari and 32 other locations)
Trial IDNCT06645951 on ClinicalTrials.gov

What this trial studies

This observational study aims to establish and manage a multicenter national database for patients diagnosed with parathyroid carcinoma or atypical parathyroid adenoma across Italy. The study will involve 33 specialized clinical centers and will collect both retrospective and prospective data over a 10-year period. Information gathered will include clinical, genetic, diagnostic, and therapeutic data to enhance understanding and management of these rare conditions. The goal is to refine clinical guidelines and improve patient outcomes through comprehensive data analysis.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with parathyroid carcinoma or atypical parathyroid adenoma.

Not a fit: Patients with other types of parathyroid tumors or those not diagnosed with parathyroid carcinoma or atypical adenoma may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved clinical management and treatment guidelines for patients with parathyroid carcinoma and atypical adenoma.

How similar studies have performed: While studies on parathyroid tumors are limited due to their rarity, the establishment of multicenter databases has shown promise in other rare conditions, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Cohort 1: parathyroid carcinoma
* Cohort 2: atypical parathyroid adenoma

Exclusion Criteria:

None

Where this trial is running

Bari and 32 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Parathyroid Gland CarcinomaParathyroid Gland Atypical AdenomaParathyroid carcinomaAtypical parathyroid adenomaRetro-prospective clinical data collectionDatabase of patients
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.