Creating 3D models of the intestine from biopsy samples

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project focuses on generating a biocollection of 3D intestinal organoids derived from digestive biopsies, which will be characterized alongside associated health data. The organoids aim to replicate the functional complexity of the human intestine, providing a more accurate model for studying digestive diseases such as inflammatory bowel disease. By using these organoids, researchers hope to screen potential therapeutic molecules and better understand the cellular and molecular mechanisms involved in these conditions. The study involves collecting additional biopsies during routine endoscopy procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects aged 18 to 75 years
* Subject undergoing endoscopy as part of the standard of care with the need to take digestive biopsy samples
* Subject having signed a free and informed consent in writing

Exclusion Criteria:

* Subjects under legal protection (safeguard of justice, curatorship or guardianship) or deprived of liberty.
* Anticoagulant treatment and anti-platelet treatment (except for aspirin 75 mg)

Where it's running

• CHU de RENNES-Service des Maladies de l'Appareil Digestif
  Rennes, France Recruiting

Study contacts

• Principal investigator: Guillaume BOUGUEN, Professor — Rennes University Hospital
• Study coordinator: Guillaume BOUGUEN, Professor
• Email: guillaume.bouguen@chu-rennes.fr
• Phone: 2 99 28 99 72

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.