Couples HIV testing with added support to reduce drug use

Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Couples

Not applicable Interventional Hunter College of City University of New York · NCT05000866

This study tests whether adding communication training and substance use support to couples HIV testing can help male couples, where one partner is HIV negative and has a history of drug use, improve their testing outcomes and reduce drug use.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment480 (estimated)
Ages17 Years to 29 Years
SexMale
SponsorHunter College of City University of New York Academic / other
Locations2 sites (Ann Arbor, Michigan and 1 other locations)
Trial IDNCT05000866 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of two additional components aimed at enhancing couples HIV testing and counseling (CHTC) for male couples. Participants will be randomly assigned to one of four groups: standard CHTC, CHTC with communication skills training videos, CHTC with a substance use module, or CHTC with both adjunct components. The goal is to assess whether these interventions can improve outcomes related to HIV testing and reduce substance use among vulnerable male couples. The study focuses on couples where one partner is HIV negative and has a history of drug use and risky sexual behavior.

Who should consider this trial

Good fit: Ideal candidates are male couples where one partner is HIV negative, aged 17-29, has used drugs in the past 90 days, and has engaged in risky sexual behaviors.

Not a fit: Patients who do not have a main male partner, are not within the specified age range, or do not meet the substance use criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved HIV testing rates and reduced substance use among male couples, enhancing their overall health and well-being.

How similar studies have performed: Other studies have shown promise in using adjunct interventions to improve health outcomes in similar populations, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* · Have a main partner who is another male and have been in a relationship for 3 month or longer

  * One participant must be between 17 and 29; Main partner can be any age above 17.
  * One participant must be HIV negative (as confirmed by rapid test)
  * One participant must have used at least 1 drug in the past 90 days (cocaine/crack, opiates, misuse of prescription medication, stimulants, psychedelics, ecstasy, ketamine, GHB)
  * One participant must have engaged in Transmission Risk Behavior (TRB) in the past 90 days

    o Defined as Condom-less Anal Sex (CAS) with a casual partner and/or CAS with a non-monogamous or serodiscordant main partner
  * Live in the NYC or Detroit metropolitan area
  * Speak English

Exclusion Criteria:

* · Any signs of serious mental illness or cognitive deficit

  * History of IPV with their main partner and safety concerns in the current relationship.

Where this trial is running

Ann Arbor, Michigan and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Substance UseHIV Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.