Cough Augmentation to Help Weaning in Critically Ill Patients
Official title: Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients
Run by Damanhour University · NCT07722260 · Data updated 2026-11-12
This study tests whether cough augmentation techniques help critically ill, intubated adults breathe easier as they try to wean off ventilation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 88 (estimated) |
| Sponsor | Damanhour University Academic / other |
| Locations | 1 site (Damanhūr) |
| Status | Recruiting |
| Started | July 8, 2026 |
| Main results expected | October 8, 2026 |
| Study ends | November 10, 2026 |
| Registry record updated | July 23, 2026 |
| Trial ID | NCT07722260 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult, intubated patients without facial trauma or tracheostomy who require mechanical ventilation in the ICU setting.
✕Probably not a fit
Patients with facial trauma or a tracheostomy may not benefit from these cough augmentation techniques.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study examines the use of cough augmentation techniques to improve weaning outcomes in adults who are critically ill and require mechanical ventilation. Techniques such as manual assisted cough, lung volume recruitment, and mechanical insufflation-exsufflation are used to enhance airway clearance and expiratory flow. By applying these methods, researchers aim to see if patients reach weaning milestones more quickly or safely. The study focuses on adults without facial trauma or tracheostomy and takes place at the Faculty of Nursing, Damanhur University. Outcomes will inform whether cough augmentation can be a standard part of weaning protocols for this population.
Why it matters
Potential benefit: If successful, patients may wean from ventilation sooner and with fewer airway clearance complications.
How similar studies have gone: Previous research in similar populations has shown promise for cough augmentation to improve airway clearance and weaning metrics, but evidence varies by technique and context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult intubated patients * both sex Exclusion Criteria: * patient with facial trauma * patient with tracheostomy tube
Where it's running
-
Faculty of Nursing, Damanhur University
Damanhūr, Egypt Recruiting
Study contacts
- Principal investigator: sahar youness, professor — professor of critical care and emergency nursing
- Study coordinator: Alaa Mustafa, assistant professor
- Email: alaa.mustafa@nur.dmu.edu.eg
- Phone: 0201097210526
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.