Core stability and foot exercises for chronic ankle instability
Official title: Effect of Core Stability Training With Foot Exercises on Proprioception, Balance and Foot Function in Chronic Ankle Instability Patients
Run by Cairo University · NCT07731035 · Data updated 2026-11-12
This study tests whether combining core stability training with intrinsic foot muscle exercises helps improve balance, proprioception, and foot function in people with chronic ankle instability.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 44 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Al Mansurah) |
| Status | Recruiting |
| Started | May 1, 2026 |
| Main results expected | August 1, 2026 |
| Study ends | September 1, 2026 |
| Registry record updated | July 28, 2026 |
| Trial ID | NCT07731035 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–44 with chronic ankle instability (Cumberland ankle instability tool score ≤24) and at least two episodes of giving way in the prior 6 months.
✕Probably not a fit
Individuals without functional instability or those outside the defined age range or eligibility criteria may not benefit from the intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Chronic ankle instability involves ongoing mechanical and functional instability after a sprain. The trial compares four approaches: conventional therapy alone; core stability training alone; intrinsic foot muscle exercises alone; and a combination of core stability with intrinsic foot exercises added to conventional therapy. Outcomes focus on lumbar and ankle proprioception, balance, and foot function to see which protocol provides the best improvement. The study aims to inform multimodal rehabilitation strategies that address both proximal and distal factors influencing sensorimotor control. Conducted at a university outpatient clinic in Egypt, it will enroll adults aged 18–44 with a history of significant ankle sprains and functional instability.
Why it matters
Potential benefit: If successful, participants may experience improved balance, proprioception, and foot function, potentially reducing the risk of recurrent ankle sprains.
How similar studies have gone: Previous research supports multimodal rehabilitation approaches for ankle instability, but this specific combination and head-to-head comparison are relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Subjects will be selected from the outpatient clinic of Delta University hospital, Dakahlia, Egypt. 2. Both male \& female genders aged between 18 and 44 years. 3. Participants should have a history of at least one significant ankle sprain; the initial sprain must have occurred at least 12 months prior to the study enrolment and was associated with inflammatory symptoms (pain, swelling) 4. Patients having Scores on the Cumberland ankle instability tool of 24 or below 5. Participants should report at least 2 episodes of 'giving way' in the 6 months prior to the study enrolment. Episodes of giving way will be described as an incident in which the rearfoot suddenly rolled, felt weak, or lost stability; however, the individual did not sustain an ankle sprain and will have been able to continue with normal function after the incident 6. Body mass index for all groups will be ranged from 18.8-29 kg/m² Exclusion Criteria: 1. history of lower extremity surgery, lower extremity fractures, and immobilization of foot or ankle for 48 hr or longer within the previous 6 months 2. Conditions other than ankle sprain that affect balance or they are receiving ankle rehabilitation at the time of screening. 3. Acute injury to the musculoskeletal structures of other joints of the lower extremity in the previous 3 months, which impacted joint integrity and function (ie, sprains, fractures) resulting in at least 1 interrupted day of desired physical activity
Where it's running
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out-patient clinic, faculty of physical therapy, Delta university
Al Mansurah, Egypt Recruiting
Study contacts
- Study coordinator: Asmaa Abdelnaser Atia Saad, physical therapist
- Email: asmaa.naser56@gmail.com
- Phone: 01024728414
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.