Cooling the skin to reduce pain from arterial puncture
Effect of Remote Local Peripheral Nerve Cooling on Pain of Arterial Puncture
This study is testing if cooling the skin can help reduce pain during arterial punctures for people who need this medical procedure.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Sex | All |
| Sponsor | The Second Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Trial ID | NCT06838572 on ClinicalTrials.gov |
What this trial studies
This project recruits volunteers to investigate the effects of cooling the superficial skin over the axillary brachial plexus on pain experienced during arterial puncture. The study aims to explore how local peripheral nerve cooling can provide a controllable and reversible analgesic effect, potentially offering a new non-pharmaceutical method for pain relief. Participants will be subjected to different skin cooling temperatures (20°C, 15°C, and 8°C) and compared to a control group with no cooling. The goal is to assess the efficacy of this approach in reducing pain associated with common medical procedures.
Who should consider this trial
Good fit: Ideal candidates are right-handed adults aged 18 to 65 who require invasive arterial blood pressure monitoring and meet specific health criteria.
Not a fit: Patients with a history of musculoskeletal, vascular, neurological, or psychiatric disorders, as well as those with systemic diseases or recent analgesic use, may not benefit from this study.
Why it matters
Potential benefit: If successful, this method could provide a safe and effective non-drug option for managing pain during arterial punctures.
How similar studies have performed: While the approach of using local peripheral nerve cooling is innovative, similar studies have shown promise in using temperature modulation for pain relief.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 18 \~ 65 years old; 2. ASA I-II level; 3. Patients with perioperative invasive arterial blood pressure monitoring; 4. Right-handed; 5. Allen test was normal (palm color quickly turned red or returned to normal within 10 seconds after release of ulnar artery pressure); 6. Participate voluntarily and be able to understand and sign informed consent. Exclusion Criteria: 1. Patients with a history of musculoskeletal, vascular, neurological or psychiatric disorders; 2. Patients with a history of diabetes or other systemic diseases 3. Patients who used any analgesic medication within the month before and during the study; 4. Patients with a history of smoking, alcohol or drug addiction; 5. Paraesthesia, scar, redness, damage, rash, etc. exist in the skin of the patient in the test area; 6. Patients whose surgical area overlaps with the cooling treatment or puncture area; 7. Female subjects are menstruating.
Where this trial is running
Chongqing, Chongqing Municipality
- The Second Affiliated Hospital of Chongqing Medical University — Chongqing, Chongqing Municipality, China (Recruiting)
Study contacts
- Study coordinator: He Huang, ph.D
- Email: huanghe@cqmu.edu.cn
- Phone: 86+13708385559
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.