Cooling the skin to reduce pain from arterial puncture

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project recruits volunteers to investigate the effects of cooling the superficial skin over the axillary brachial plexus on pain experienced during arterial puncture. The study aims to explore how local peripheral nerve cooling can provide a controllable and reversible analgesic effect, potentially offering a new non-pharmaceutical method for pain relief. Participants will be subjected to different skin cooling temperatures (20°C, 15°C, and 8°C) and compared to a control group with no cooling. The goal is to assess the efficacy of this approach in reducing pain associated with common medical procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 18 \~ 65 years old;
2. ASA I-II level;
3. Patients with perioperative invasive arterial blood pressure monitoring;
4. Right-handed;
5. Allen test was normal (palm color quickly turned red or returned to normal within 10 seconds after release of ulnar artery pressure);
6. Participate voluntarily and be able to understand and sign informed consent.

Exclusion Criteria:

1. Patients with a history of musculoskeletal, vascular, neurological or psychiatric disorders;
2. Patients with a history of diabetes or other systemic diseases
3. Patients who used any analgesic medication within the month before and during the study;
4. Patients with a history of smoking, alcohol or drug addiction;
5. Paraesthesia, scar, redness, damage, rash, etc. exist in the skin of the patient in the test area;
6. Patients whose surgical area overlaps with the cooling treatment or puncture area;
7. Female subjects are menstruating.

Where it's running

• The Second Affiliated Hospital of Chongqing Medical University
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: He Huang, ph.D
• Email: huanghe@cqmu.edu.cn
• Phone: 86+13708385559

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.