Continuous monitoring of microvascular connections: an observational study

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study at Mayo Clinic aims to determine whether audible blood-flow signals from a Doppler monitor can be captured and converted into a visual signal. The goal is to provide clinicians with an additional way to track free flap perfusion after head and neck reconstructive surgery. Eligible participants are adults scheduled for free flap procedures who will receive an implanted Doppler device and have arterial Doppler waveforms available for analysis. Data will be collected non-interventionally during standard postoperative follow-up to explore the feasibility of signal conversion and potential implications for flap monitoring.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Scheduled for free flap surgery and planned to have an implanted doppler monitor
* Arterial Doppler waveforms available for analysis
* Able and willing to sign consent and return for clinical follow up
* Age ≥ 18 years

Exclusion Criteria:

* Prior head and neck surgery within the region where surgeons plan to identify donor vessels ≤ 365 days prior to registration

Where it's running

• Mayo Clinic in Rochester
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Kathryn M. Van Abel, MD — Mayo Clinic in Rochester
• Study coordinator: Clinical Trials Referral Office
• Email: mayocliniccancerstudies@mayo.edu
• Phone: 855-776-0015

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Identifying biomarkers for HPV-related oropharyngeal cancer

  This study is trying to find specific markers in blood and saliva that can help identify HPV-related throat cancer in patients who are already diagnosed with advanced stages of the disease.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT06356272

• Blood test for cancer DNA in head and neck cancer patients

  This study is testing if a blood test that looks for cancer DNA can help doctors understand how head and neck cancer behaves before and after surgery, and see if it can predict if the cancer will come back.

  Recruiting UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT04099290

• What the Mayo Clinic is learning from blood clot tests in allergic reactions

  This study tests whether real-time blood clotting markers can help understand and predict the severity of allergic reactions and anaphylaxis in patients 12 and older.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07905911

• Atrial Arrhythmia AI-Powered Post-Ablation Predictor Pilot

  This pilot study tests whether AI models using non-invasive heart-mapping data can predict how patients with atrial arrhythmias respond after ablation.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07904377

• A Community Approach to Boost Cervical Cancer Screening for Hispanic and East African Immigrant Women

  The study tests a community-based program that offers self-collection HPV tests and information to Hispanic and East African immigrant women to see if screening rates improve.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07890402

• Point-of-care AI spectroscopy test to triage vulvar lesions

  This pilot study tests whether a handheld AI-powered spectroscopy device can help triage vulvar lesions in adults who are planning surgical removal.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07886203

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.