Continuous glucose monitoring to help adults with prediabetes manage blood sugar

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with prediabetes will wear a small continuous glucose monitor (CGM) sensor on the back of the arm and view glucose data on their phone using the FreeStyle LibreLink app, while a comparison group receives traditional health coaching. The team will compare behavioral changes and short-term health outcomes between the CGM group and the coaching group and will collect feasibility data on using CGM in this population. Eligible participants are Singapore citizens or permanent residents aged 21–69 with prediabetes by fasting glucose or 2-hour OGTT criteria, able to use the app, and not pregnant or cognitively impaired. This is an initial pilot effort to see if CGM use is practical and whether real-time glucose feedback can influence lifestyle choices in people with prediabetes.

Why it matters

Who can join: the full rules

Patient Participants

Inclusion Criteria:

1. Singaporean Citizen or Permanent Resident
2. Age 21 - 69 years old
3. Clinical diagnosis of prediabetes defined as a fasting glucose of 6.1-6.9 mmol/L and/or 2-hour glucose level of 7.8-11.0 mmol/L after an oral glucose tolerance test (Appropriate Care Guide, 2021)

   a. Can be conservatively managed, or medically managed with metformin
4. Owns a mobile phone that can download the Singapore FreeStyle LibreLink App
5. Expressed willingness to use participate in the study, use the devices according to the study protocol during the study period, and to sign informed consent.

Exclusion Criteria:

1. Pregnant or planned pregnancy within the next six months
2. Physical limitation that prevents the patient from engaging in physical exercise
3. Cognitively impaired based on diagnosis of dementia or mild cognitive impairment (MCI) in the electronic health records (EHR)
4. Not adequately proficient in English
5. Currently enrolled in another study or program that involves weight loss or dietary modifications, or novel therapeutic drug or device
6. Planned surgery in the next six months
7. Not able to use smartphone or the Singapore FreeStyle LibreLink App despite coaching
8. Any end-stage disease with life prognosis of \< 2 years
9. Patients who are not willing or are not able to commit to the entire study program

Healthcare Providers (HCP) Participants HCPs from Pasir Ris Polyclinic who self-reported to have treated adults with prediabetes will be enrolled for the interviews.

Where it's running

• Pasir Ris Polyclinic
  Singapore, Singapore Recruiting
• Pasir Ris Polyclinic
  Singapore, Singapore Recruiting

Study contacts

• Principal investigator: Ying Jun Lim, BScHons, MD — SingHealth Polyclinics
• Study coordinator: Cindy MY Wong, MBBS, Mmed (Family Medicine)
• Email: cindy.wong@singhealth.com.sg
• Phone: +6563507600

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.