Continuous ESP Block for Analgesia After CABG Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, blinded phase 3 trial, patients undergoing CABG with CPB receive an ESP block at the T4 level after anesthesia induction. They are randomized to receive ropivacaine or saline as the block solution, with catheter-based continuous infusion and PCA for maintenance analgesia. All participants also receive standard multimodal analgesia, and postoperative analgesia is guided by protocol. Outcomes focus on analgesia effectiveness and safety in the cardiac surgical setting. The study uses ultrasound guidance for block placement and standardized perioperative care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Consent to the free and informed consent term.
* Patient undergoing coronary artery bypass graft surgery with cardiopulmonary bypass (CPB).
* Preserved left ventricular global function (LVEF \> 50%).

Exclusion Criteria:

* Moderate or severe valvular dysfunction.
* Previous anterior sternotomy.
* Known allergy to the study drugs.
* Complications during catheter insertion or block placement.
* Pre-existing diagnosed chronic pain under treatment.
* Concomitant use of drugs with a long half-life (induction and anesthetic maintenance doses will be standardized; patients taking medications with a long half-life are excluded to prevent bias in outcome assessment).
* Concomitant administration of Magnesium Sulfate.

Where it's running

• InCor
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: JOAO ALBERTO PASTOR de OLIVEIRA, MD
• Email: joaoalbertopastor@yahoo.com.br
• Phone: +5511991700431

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.